Enhancing the Vascularization Properties of Skin Tissue

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$1,585,339.00
Award Year:
2007
Program:
SBIR
Phase:
Phase II
Contract:
2R44AG026903-02A1
Agency Tracking Number:
AG026903
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
STRATATECH CORPORATION
505 SOUTH ROSA ROAD, SUITE 169, MADISON, WI, 53719
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
160392168
Principal Investigator:
ALLEN COMER
(608) 441-2759
ACOMER@STRATATECHCORP.COM
Business Contact:
ALLEN COMER
() -
rbarnard@stratatechcorp.com
Research Institution:
n/a
Abstract
DESCRIPTION (provided by applicant): To date no biological treatment options specifically targeting the hypoxic nature of chronic wounds have been developed and marketed. While administration of individual angiogenic factors may stimulate some aspects of a ngiogenesis, the simultaneous expression of multiple factors is required to promote morphologically and functionally normal vessels. In this Phase II study, we propose to characterize a human keratinocyte cell line genetically-modified to coordinately expr ess elevated levels of multiple therapeutic factors. Advances in ex vivo genetic engineering of a patented human keratinocyte cell line at Stratatech Corporation has made it uniquely positioned to complete this work. If successful, the proposed research wi ll ultimately lead to the development and commercialization of improved treatments to promote the healing of chronic wounds and other severe skin defects.

* information listed above is at the time of submission.

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