USE OF MATED RECIPIENTS AS AN AID TO EMBRYO TRANSFER IN SWINE

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1988
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Agency Tracking Number:
7966
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Sullivan Veterinary Clinic
713 E Jackson, Sullivan, IL, 61951
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
PROBLEMS ASSOCIATED WITH COMMERCIAL EMBRYO TRANSFER IN SWINE INCLUDE DIFFICULTIES IN THE SELECTION OF SUITABLE RECIPIENTS, REDUCED PREGNANCY RATES, REDUCED REPRODUCTIVE EFFICIENCY AND REDUCED ACCEPTANCE BY THE COMMERCIAL SWINE INDUSTRY. TRANSPLANTATION OF DISTINGUISHABLE EMBRYOS INTO MATED RECIPIENTS MAY SIMPLIFY RECIPIENT PREPARATION, IMPROVE REPRODUCTIVE EFFICIENCY AND INCREASE BOTH THE ACCEPTANCE ANDEFFICIENCY OF COMMERCIAL EMBRYO TRANSFER IN SWINE. EMBRYOS WERE OBTAINED BY TECHNIQUES COMMONLY UTILIZED FOR COMMERCIAL EMBRYO TRANSFER SERVICES. MATED RECIPIENTS WERE SELECTED WITHIN THE REGULAR BREEDING SCHEME OF A COMMERCIAL PIG COMPLEX FOR STAGES 2-3 DAYS YOUNGER THAN THE USUSAL SYNCHRONIZED UTERINE ENDOMETRIUM OF UNMATED RECIPIENTS. REDUCED NUMBERS OF DAY 6-7 PROCINE EMBRYOS (BLASTOCYSTS) WERE TRANSPLANTED INTO DAY 4 MATED RECIPIENTS FOLLOWING PROCEDURES UTILIZED FOR COMMERCIAL EMBRYO TRANSFER IN SWINE. WHEN FOLLOWING THIS PROTOCOL IT IS POSSIBLE THAT THE MORE DEVELOPED EMBRYOS SYNTHESIZE ESTROGEN FIRST, THUS ADVANCING THE SECRETORY PATTERNS OF THE UTERUS, RESULTING IN IMPROVEMENT OF THE EFFICIENCY OF THE OFFSPRING PRODUCED PER EMBRYOS TRANSFERRED.

* information listed above is at the time of submission.

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