EXCIMER LASER PHOTOREFRACTIVE KERATECTOMY IN ANIMALS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$49,625.00
Award Year:
1990
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
13868
Agency Tracking Number:
13868
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
21 Hickory Dr, Waltham, MA, 02154
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
David F Muller
(617) 890-1234
Business Contact:
() -
Research Institution:
n/a
Abstract
A PREVIOUSLY DEVELOPED 193-NM EXCIMER LASER SYSTEM, THE EXCIMED UV200LA, WILL BE USED TO PERFORM PHOTOREFRACTIVE KERATECTOMY USING TWO DIFFERENT TREATMENT TECHNIQUES. THE CLINICAL RESULTS OF THE EXCIMED UV200LA WITH AN ELECTRONICALLY DRIVEN IRIS APERTURE DELIVERY SYSTEM WILL BE COMPARED TO AN EXCIMED UV200LA WITH A FIXED-BEAM DIAMETER USED IN CONJUNCTION WITH AN ABLATABLE MASK. DEVELOPMENT OF THE ABLATABLE MASK WILL BE CARRIED OUT, AND A RANGE OF OPERATING PARAMETERS FOR PERFORMING PHOTOREFRACTIVE KERATECTOMY WITH THE ABLATABLE MASK WILL BE DETERMINED IN MATERIAL MODELS, IN VITRO AND IN VIVO. ANALYSIS OF THE DATA COLLECTED IN RABBITS AND MONKEYS WILL DETERMINE IF THE ABLATABLE MASK TECHNIQUE WILL BE USED IN FURTHER HUMAN CLINICAL TRIALS OF PHOTOREFRACTIVE KERATECTOMY.

* information listed above is at the time of submission.

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