THE LONG-TERM OBJECTIVE IS SAFE AND EFFECTIVE TREATMENT OF OCULAR MELANOMA, BY SURGICAL EXCISION UTILIZING ND:YAG AND/OR ARGON LASER ENERGY.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$39,633.00
Award Year:
1985
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
3174
Agency Tracking Number:
3174
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
33a Great Valley Parkway, Malvern, PA, 19355
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
JOHN OSBORN
PRINCIPAL INVESTIGATOR
(215) 647-8277
Business Contact:
() -
Research Institution:
n/a
Abstract
THE LONG-TERM OBJECTIVE IS SAFE AND EFFECTIVE TREATMENT OF OCULAR MELANOMA, BY SURGICAL EXCISION UTILIZING ND:YAG AND/OR ARGON LASER ENERGY. THE SPECIFIC AIMS OF THIS STUDY ARE: 1. THE DEVELOPMENT OF CONTACT SAPPHIRE CERAMIC PROBES, 2. FIBER OPTIC CONNECTING CABLES FOR DELIVERY OF LASER ENERGY TO PROBE, AND 3. TO STUDY THE TISSUE EFFECTS OF CONTACT LASER SURGERY IN RABBIT EYES, BOTH CLINICALLY AND HISTOLOGICALLY. DELIVERY OF ND:YAG AND ARGON LASER ENERGY WITH SAPPHIRE CERAMIC PROBE BY DIRECT CONTACT WITH TUMOR TISSUE RESULTS IN MORE ACCURATE PLACEMENT OF ENERGY (DEPTH AND LATERAL PENETRATION) PRODUCING LESS SURROUNDING TISSUE DAMAGE AND 75% LESS ENERGY NECESSARY THAN NONCONTACT DELIVERY. THE CONTACT SAPPHIRE CERAMIC PROBES WILL BE DEVELOPED AND FABRICATED BY SLT, JAPAN. THE LAUNCH OPTICS AND CONNECTING CABLES WILL BE DEVELOPED AND FABRICATED BY SLT, USA. THE SURGICAL APPLICATION AND TISSUE EFFECTS IN RABBITS WILL BE STUDIED BY CONSULTANTS AT THE WILLS EYE HOSPITAL. THE RESULTS OF THIS WILL ENABLE US TO GO TO PHASE II FOR EXPERIMENTAL REMOVAL OF UVEAL TUMORS IN RABBITS AND EVENTUALLY, WITH THE DEVELOPMENT OF THE STUDY, FOR TREATMENT IN HUMANS. THE COMMERCIAL AVAILABILITY OF THE LAUNCH OPTICS,

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government