Synaptic Pharmaceutical Corp.

Company Information

Company Name
Synaptic Pharmaceutical Corp.
Address
215 COLLEGE RD
Paramus, NJ, 07652
Phone
1 201-261-1331
URL
n/a
DUNS
n/a
Number of Employees
n/a

Award Totals

PROGRAM/PHASE
AWARD AMOUNT ($)
NUMBER OF AWARDS
SBIR Phase I
$1,028,750.00
16
SBIR Phase II
$2,607,846.00
5
Chart code to be here

Award List

  1. CLONING OF THE SEROTONIN 5-HT1B AND 5-HT1D RECEPTORS

    Amount: $50,000.00

    THE 5-HT1B AND 5-HT1D RECEPTORS APPEAR TO PLAY A SIGNIFICANTROLE IN AT LEAST FOUR MEDICALLY IMPORTANT PROCESSES: THERMOREGULATION, APPETITE CONTROL, ANXIETY, AND OBSESSIVE-COMPULSIVE DISORDERS. THESE ...

    SBIR Phase I 1989 Department of Health and Human Services
  2. ASSAY SYSTEM FOR CLONED GI-COUPLED RECEPTORS

    Amount: $400,293.00

    MOLECULAR CLONING AND HETEROLOGOUS EXPRESSION OF NEUROTRANSMITTER RECEPTOR GENES PROVIDE A MEANS TO STUDY THESE SITES OF DRUG ACTION FREE FROM THE COMPLEXITIES OF INTACT NEURAL TISSUE. THESE HETEROLOG ...

    SBIR Phase II 1991 Department of Health and Human Services
  3. CLONING OF THE SEROTONIN 5-HT1P RECEPTOR

    Amount: $479,956.00

    THE SEROTONIN 5-HT1P RECEPTOR HAS BEEN EXTENSIVELY CHARACTERIZED IN THE ENTERIC NERVOUS SYSTEM WHERE IT FUNCTIONS IN THE REGULATION OF GASTROINTESTINAL MOTILITY. IN ADDITION, 5-HT1P-LIKE BINDING SITES ...

    SBIR Phase II 1991 Department of Health and Human Services
  4. EXPRESSION CLONING OF THE DOPAMINE DI RECEPTOR

    Amount: $477,597.00

    DOPAMINERGIC NEUROTRANSMISSION PLAYS A SIGNIFICANT ROLE IN PSYCHIATRIC AND EXTRAPYRAMIDAL DISORDERS, ENDOCRINE FUNCTION, AND VASODILATION. TO BETTER UNDERSTAND THE DOPAMINE D1 RECEPTOR AS A POTENTIAL ...

    SBIR Phase II 1991 Department of Health and Human Services
  5. MOLECULAR CLONING OF POIATE RECEPTOR SUBTYPES

    Amount: $50,000.00

    OPIATE RECEPTORS, WHICH ARE IMPORTANT PHARMACOLOGICAL TARGETS FOR ANALGESIA AND FOR THE CONTROL OF DRUG ADDICTION,HAVE NOT BEEN CLONED AND THEIR AMINO ACID SEQUENCES ARE UNKNOWN. RECENT WORK INDICATES ...

    SBIR Phase I 1991 Department of Health and Human Services
  6. CHARACTERIZATION OF CLONIDINE DISPLACING SUBSTANCE

    Amount: $50,000.00

    RECENT MOLECULAR PHARMACOLOGICAL STUDIES HAVE INDENTIFIED A NEW RECEPTOR CLASS WHICH RESEMBLES ALPHA 2 ADRENOCEPTORS BUT BECAUSE OF SUBTLE DIFFERENCE HAS BEEN NAMED BY A VARIETY OF DESCRIPTORS INCLUDI ...

    SBIR Phase I 1992 Department of Health and Human Services
  7. FUNCTIONAL ASSAY SYSTEMS FOR HUMAN ADRENERGIC RECEPTORS

    Amount: $50,000.00

    ALPHA-1 ADRENERGIC DRUGS HAVE RECENTLY SHOWN GREAT POTENTIAL IN THE TREATMENT OF BPH. THE EXISTENCE OF RECEPTOR HETEROGENEITY WITHIN THE ALPHA-1 ADRENOCEPTORS SUGGESTS THE POSSIBILITY OF IMPROVING DRU ...

    SBIR Phase I 1992 Department of Health and Human Services
  8. Camp-Stimulatory Serotonin Receptors

    Amount: $78,750.00

    Activation of a subset of serotonin receptors evokes physiological responses characteristic ofadenylate cyclase stimulation in a wide variety of tissues: neuronal depolarization, relaxation of smoothm ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. New Pharmacological Tools for Alpha Adrenergic Receptors

    Amount: $750,000.00

    Alpha adrenoceptors serve numerous functions throughout the peripheral and central nervoussystems. Chemical modulators of these receptors have a variety of potential therapeutic applications,including ...

    SBIR Phase II 1996 Department of Health and Human Services
  10. NPY-Like Agonists and Antagonists for CNS YL Receptors

    Amount: $50,000.00

    Neuropeptide Y (NPY) activates at least three receptor subtypes with central and peripheral localization (Y1, Y2, and Y3). The human Y1 receptor, linked to various CNS disorders including anxiety, dep ...

    SBIR Phase I 1993 Department of Health and Human Services

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