METHODOLOGY IN CANCER CLINICAL TRIALS

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 4823
Amount: $28,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1986
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Takima West Corp
100 Eastowne Drive, Suite 200, Chapel Hill, NC, 27514
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 DR NORMAN L JOHNSON
 PRINCIPAL INVESTIGATOR
 (919) 493-8574
Business Contact
Phone: () -
Research Institution
N/A
Abstract
THE TECHNICAL PROBLEM ADDRESSED BY THIS PROJECT IS THE DEVELOPMENT OF INTERACTIVE SOFTWARE FOR STATE-OF-THE-ART STATISTICAL METHODOLOGY APPLICABLE TO CANCER CLINICAL TRIALS. THE SPECIFIC OBJECTIVE IS TO USE TOOLS AVAILABLE IN THE SAS SYSTEM FOR MICROCOMPUTERS TO PACKAGE THE EXISTINGSOFTWARE IN SUCH A WAY THAT THE ANALYST CAN MOVE QUICKLY ANDINTERACTIVELY FROM GRAPHICAL DATA DISPLAYS AND MODEL FORMULATION TO GRAPHICAL MODEL CHECKING AND MODEL VALIDATION. TO MEET THIS OBJECTIVE, TAKIMA WEST CORPORATIONWILL CRITICALLY EXAMINE THS USE OF THE SAS MACRO LANGUAGE, THE DISPLAY MANAGER, THE PROCEDURE MENU SYSTEM, AND THE SAS AF PRODUCT. RESEARCHERS WILL ALSO STUDY HOW INDIVIDUAL PRO-CEDURES CAN BE MADE MORE INTERACTIVE. DURING THIS PHASE I PROJECT, THE SAS DEVELOPMENT TOOLS WILL BE SELECTED. DESIGNOF HOW THESE TOOLS SHOULD BE USED WILL BE PREPARED IN A PHASE II STUDY. THIS PROJECT WILL ALLOW RESEARCHERS TO ANALYZE DATA MORE QUICKLY AND THOROUGHLY THAN CAN BE DONE ATPRESENT. BETTER MODEL FORMULATION, MORE ACCURATE INFERENCES, AND EASIER INTERPRETATION OF STATISTICAL ANALYSES ARE THE FINAL GOALS OF THESE EFFORTS.

* information listed above is at the time of submission.

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