WE PROPOSE TO IMPLEMENT IN COMPUTER CODE, AND TEST BY COMPUTER SIMULATION, A NEW, FAST ULTRASOUND IMAGING AND TISSUE CHARACTERIZATION ALGORITHM, BASED ON OUR SOLUTION OF THE INVERSE SCATTERING PROBLEM, FOR APPLICATION TO MEDICAL DIAGNOSIS.

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1985
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
3103
Agency Tracking Number:
3103
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
1155 East 300 South No. 8., Salt Lake City, UT, 84102
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
MICHAEL J. BERGGREN
PRINCIPAL INVESTIGATOR
(801) 583-2679
Business Contact:
() -
Research Institution:
n/a
Abstract
WE PROPOSE TO IMPLEMENT IN COMPUTER CODE, AND TEST BY COMPUTER SIMULATION, A NEW, FAST ULTRASOUND IMAGING AND TISSUE CHARACTERIZATION ALGORITHM, BASED ON OUR SOLUTION OF THE INVERSE SCATTERING PROBLEM, FOR APPLICATION TO MEDICAL DIAGNOSIS. IMPLEMENTATION OF OUR ALGORITHM WOULD PERMIT COMPUTATION OF THE INVERSE SCATTERING SOLUTION OF THE EXACT (NOT LINEARIZED) HELMHOLTZ WAVE EQUATION FOR A VISCO-ELASTIC FLUID MODEL OF TISSUE WITH INHOMOGENEOUS DENSITY (D), SPEED OF SOUND (C), AND ABSORPTION (A), PROPERTIES. THIS IMAGE SOLUTION IS ROBUST (NOISE TOLERANT AND STABLE), HAS EXTREMELY HIGH SPATIAL RESOLUTION APPROACHING 1/2 TO 1/4 MM (I.E., NEAR 1/2 WAVE LENGTH), AND PROVIDES HIGHLY ACCURATE QUANTITATIVE IMAGES OF THE ABOVE DEFINED TISSUE PARAMETERS D, C, AND A. THIS IS AN IMPROVEMENT OF A FACTOR OF 4 TO 8 OVER PRESENT NONQUANTITATIVE B-SCAN TECHNOLOGY. DURING PHASE I WE PROPOSE TO SIMULATE SCATTERING DATA FROM A RESOLUTION PHANTOM AND FROM A BLOOD VESSEL SURROUNDED WITH TYPICAL TISSUES. THE PERFORMANCE OF THE ALGORITHM WILL BE EVALUATED IN TERMS OF ACCURACY, RESOLUTION, ROBUSTNESS, AND CONVERGENCE RATE. THESE RESULTS WOULD BE EVALUATED USING LABORATORY DATA FROM REAL ORGANS AND A NEW CLINICAL

* information listed above is at the time of submission.

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