Formulation of a Neutralizing Skin Protectant (NSP)

Award Information
Agency: Department of Defense
Branch: Office for Chemical and Biological Defense
Contract: W81XWH-05-C-0131
Agency Tracking Number: C051-118-0061
Amount: $749,835.00
Phase: Phase II
Program: SBIR
Awards Year: 2006
Solicitation Year: 2005
Solicitation Topic Code: CBD05-118
Solicitation Number: 2005.1
Small Business Information
15 Acorn Park, Cambridge, MA, 02140
DUNS: 111046152
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Emily Reichert
 Sr Scientist, App. Chem &
 (617) 498-5416
Business Contact
 Renee Wong
Title: Contracting Officer
Phone: (617) 498-5655
Research Institution
Currently there is a need for a pre-exposure decontaminating skin cream that will neutralize chemical warfare agents (CWA) on contact. Current approaches to this problem cannot both dissolve a CWA challenge and neutralize the agent into less toxic products before it reaches the skin surface. Our Phase II Technical Approach will result in the development of an innovative Neutralizing Skin Protectant (NSP). The NSP will employ physiochemical means to protect exposed skin from chemical agents while solubilizing both an active moiety and the CWA, enabling a neutralization reaction to occur within the matrix. In Phase II we will create topical formulation prototypes which have been optimized based on the results of skin permeation studies. The Phase II work will build on Phase I results demonstrating the efficacy of our approach against surrogates.

* Information listed above is at the time of submission. *

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