Formulation of a Neutralizing Skin Protectant (NSP)

Award Information
Agency:
Department of Defense
Branch
Office for Chemical and Biological Defense
Amount:
$749,835.00
Award Year:
2006
Program:
SBIR
Phase:
Phase II
Contract:
W81XWH-05-C-0131
Award Id:
74259
Agency Tracking Number:
C051-118-0061
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
15 Acorn Park, Cambridge, MA, 02140
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
111046152
Principal Investigator:
Emily Reichert
Sr Scientist, App. Chem &
(617) 498-5416
reichert.emily@tiaxllc.com
Business Contact:
Renee Wong
Contracting Officer
(617) 498-5655
wong.renee@tiaxllc.com
Research Institute:
n/a
Abstract
Currently there is a need for a pre-exposure decontaminating skin cream that will neutralize chemical warfare agents (CWA) on contact. Current approaches to this problem cannot both dissolve a CWA challenge and neutralize the agent into less toxic products before it reaches the skin surface. Our Phase II Technical Approach will result in the development of an innovative Neutralizing Skin Protectant (NSP). The NSP will employ physiochemical means to protect exposed skin from chemical agents while solubilizing both an active moiety and the CWA, enabling a neutralization reaction to occur within the matrix. In Phase II we will create topical formulation prototypes which have been optimized based on the results of skin permeation studies. The Phase II work will build on Phase I results demonstrating the efficacy of our approach against surrogates.

* information listed above is at the time of submission.

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