In-vivo measurement of gas bubble formation

Award Information
Agency:
Department of Defense
Branch
Navy
Amount:
$69,955.00
Award Year:
2007
Program:
STTR
Phase:
Phase I
Contract:
N00014-07-M-0428
Award Id:
83485
Agency Tracking Number:
N074-038-0269
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
15 Acorn Park, Cambridge, MA, 02140
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
111046152
Principal Investigator:
VernonShrauger
Associate Principal
(617) 498-5172
shrauger.vern@tiaxllc.com
Business Contact:
ReneeWong
Contracting Officer
(617) 498-5655
wong.renee@tiaxllc.com
Research Institute:
HARVARD UNIV.
David A Weitz
Pierce Hall
29 Oxford St
Cambridge, MA, 2138
(617) 496-2843
Nonprofit college or university
Abstract
We propose the development of an in-vivo bubble detection system that will measure the evolution of gas bubbles in biological tissue and blood. Our approach utilizes established commercial technology with advanced imaging techniques to permit visualization of microbubble formation without entering the body. The sensor will be able to quantify the size and density of bubbles as they evolve and will be used as a tool to help study microbubble formation in an effort to correlate them to decompression sickness (DCS). The technology allows the proposed sensor to be lightweight, low-power, compact, wearable and self-contained. With an eventual DCS correlation, the portability and method of the proposed bubble sensor will ultimately enable personalized dive parameter calculation so divers can operate optimally and safely within their physiological limits.

* information listed above is at the time of submission.

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