Compact device for quantitative measurement of in-vivo gas bubble formation

Award Information
Agency:
Department of Defense
Branch
Navy
Amount:
$500,125.00
Award Year:
2008
Program:
STTR
Phase:
Phase II
Contract:
N00014-08-C-0728
Agency Tracking Number:
N074-038-0269
Solicitation Year:
2007
Solicitation Topic Code:
N07-T038
Solicitation Number:
n/a
Small Business Information
TIAX LLC
15 Acorn Park, Cambridge, MA, 02140
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
111046152
Principal Investigator:
Vernon Shrauger
Associate Principal
(617) 498-5172
shrauger.vern@tiaxllc.com
Business Contact:
Renee Wong
Contracting Officer
(617) 498-5655
wong.renee@tiaxllc.com
Research Institution:
HARVARD UNIV.
David A Weitz
Pierce Hall
29 Oxford Street
Cambridge, MA, 2138
(617) 496-2843
Nonprofit college or university
Abstract
We propose to live animal test and continue the refinement of our in-vivo bubble detection system, which quantitatively measures the evolution of gas bubbles in biological tissue and fluid. Our approach utilizes established commercial technology with advanced imaging techniques to permit visualization of microbubble formation without entering the body. The Phase I developed proof-of-concept will be combined with electronic signal processing to quantify the size and density of bubbles as they evolve. We will reduce our laboratory proof-of-concept to a compact prototype that we envision will be used as a tool to help study microbubble formation in an effort to correlate them to the onset of decompression sickness (DCS). The compact prototype will demonstrate the lightweight, low-power, and self-contained nature of the technology. With an eventual DCS correlation, the portability and method of the proposed bubble sensor will ultimately enable personalized dive parameter calculation so divers can operate optimally and safely within their physiological limits.

* information listed above is at the time of submission.

Agency Micro-sites

US Flag An Official Website of the United States Government