Triplex Pharmaceutical

Company Information

Company Name
Triplex Pharmaceutical
Address
9391 Grogans Mill Road
The Woodlands, TX, 77380
Phone
n/a
URL
n/a
DUNS
n/a
Number of Employees
n/a
Hubzone Owned:
N
Minority Owned:
Y
Woman Owned:
N

Award Totals

PROGRAM/PHASE
AWARD AMOUNT ($)
NUMBER OF AWARDS
SBIR Phase I
$953,849.00
14
Chart code to be here

Award List

  1. ANTI-HSV-1 ACTION OF TRIPLEX FORMING OLIGONUCLEOTIDES

    Amount: $49,095.00

    THE AIM OF THIS PROJECT IS TO TEST THE FEASIBILITY OF USING TRIPLEX FORMING OLIGONUCLEOTIDES AS ANTIVIRAL AGENTS AGAINSTHERPES SIMPLEX VIRUS TYPE 1. OLIGONUCLEOTIDES HAVE LONG BEEN KNOWN TO BE CAPABLE ...

    SBIR Phase I 1991 Department of Health and Human Services
  2. MODIFIED NUCLEOSIDES IN TRIPLEX FORMING OLIGONUCLEOTIDES

    Amount: $50,000.00

    THE PRIMARY GOAL OF THIS STUDY IS TO CHEMICALLY REFINE A CLASS OF SEQUENCE-SPECIFIC, DNA BINDING, TRIPLE HELIX-FORMING OLIGONUCLEOTIDES (TFOS). THE UNIQUE FEATURE OF THESE TFOS IS THAT BINDING OF THE ...

    SBIR Phase I 1992 Department of Health and Human Services
  3. ANTI HIV-1 ACTIVITY OF TRIPLEX FORMING OLIGNUCLEOTIDES

    Amount: $50,000.00

    ANTIVIRAL AGENTS FOR THE TREATMENT FOR HUMAN IMMUNODEFICIENCY VIRUS (HIV-1) ARE DEARLY IN GREAT NEED. WE HAVE SYNTHESIZED AND DONE PRELIMINARY EXPERIMENTS WITH A TRIPLE HELIX FORMING OLIGONUCLEOTIDE D ...

    SBIR Phase I 1992 Department of Health and Human Services
  4. IMPROVED TRIPLE HELIX FORMING OLIGONUCLEOTIDES

    Amount: $49,998.00

    TRIPLE HELIX FORMING OLIGONUCLEOTIDES (TFOS) OFFER THE POTENTIAL TO SPECIFICALLY MODULATE EXPRESSION OF ANY GENE IN A SEQUENCE DEPENDENT MANNER. AT PRESENT, TFOS CAN BE DESIGNED TO BIND TO CERTAIN TAR ...

    SBIR Phase I 1992 Department of Health and Human Services
  5. MODIFIED OLIGONUCLEOTIDES INTRIPLE HELIX FORMATION

    Amount: $50,000.00

    THE PRIMARY GOAL OF THIS STUDY IS TO CHEMICALLY REFINE A CLASS OF SEQUENCE-SPECIFIC, DNA BINDING, TRIPLE HELIX-FORMING OLIGONUCLEOTIDES (TFOS). THE UNIQUE FEATURE OF THESE TFOS IS THAT BINDING OF THE ...

    SBIR Phase I 1992 Department of Health and Human Services
  6. Enhanced Efficacy of Triplex Oligonucleotides

    Amount: $50,000.00

    We will develop a novel class of therapeutics based on Triple-Helix Forming Oligonucleotides (TFOs). Attachment of lipophilic groups to anti-cancer and anti- HSV-2 TFOs will be examined to enhance the ...

    SBIR Phase I 1993 Department of Health and Human Services
  7. Triplex Inhibition of Progesterone Receptor

    Amount: $50,000.00

    Triple helix formation between duplex DNA and oligonucleotides has been observed for over twenty years for synthetic polymers and more recently for genomic DNA. Triplex formation prevents the associat ...

    SBIR Phase I 1993 Department of Health and Human Services
  8. Oligonucleotides Inhibition of HIV-1 Integrase

    Amount: $65,956.00

    Effective therapy for human immunodeficiency virus (HIV) infection remains elusive, partly dueto the fact that infected long lived cells provide a reservoir for the virus. Currently availableanti-retr ...

    SBIR Phase I 1994 Department of Health and Human Services
  9. Anti-HCMV Activity of Triple Helix-Forming Oligos

    Amount: $40,000.00

    The aim is to test the feasibility of using triple helix (triplex)-forming oligonucleotides as antiviral agents against human cytomegalovirus. Oligonucleotides have long been known to be capable of bi ...

    SBIR Phase I 1993 Department of Health and Human Services
  10. Development of a Novel Anti-HIV Oligonucleotide

    Amount: $98,800.00

    AIDS is a fatal disorder of the immune system caused by the HIV and is a widespread epidemic. The lobjective of this work is to treat human AIDS patients with a novel oligonucleotide (T30177) that haa ...

    SBIR Phase I 1995 Department of Health and Human Services

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