Alkenylguanine Analogs--A New Class of Antiviral Agent

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$100,000.00
Award Year:
1995
Program:
SBIR
Phase:
Phase I
Contract:
1 R43 AI36788-01A1,
Award Id:
29094
Agency Tracking Number:
29094
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
9391 Grogans Mill Road, The Woodlands, TX, 77380
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Arthur Lewis
() -
Business Contact:
() -
Research Institution:
n/a
Abstract
We will develop certain structure activity relationships with respect to a novel class of antiviralconduct preliminary experiments designed to define the mechanism of action for these drugs. Preliminestablished that certain alkenes, when attached to a guanine congener, provide potential antiviral atherapeutic indices against debilitating, human, DNA viral infections . We will synthesize additionaactive compounds wherein certain structural variations will be made in the unsaturated hydrocarbon mcomparison of the antiviral activity of these additional derivatives will be used to construct a hypstructural features suggesting the most promising drug candidate. Information from simultaneous studof antiviral action of these drugs will be incorporated into the development of the model.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government