TSRL, INC.

Basic Information

540 AVIS DR STE A
ANN ARBOR, MI, 48108-7906

Company Profile

n/a

Additional Details

Field Value
DUNS: 156551699
Hubzone Owned: N
Socially and Economically Disadvantaged: N
Woman Owned: N
Number of Employees: n/a


  1. Broad Spectrum Antiviral Nucleoside Phosphonate Analogs

    Amount: $997,904.00

    DESCRIPTION provided by applicant The Working Group for Civilian Biodefense reviewed potential biological threat agents and listed those considered to pose the greatest threat to the civilian popul ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of HealthDepartment of Health and Human Services
  2. Nucleoside Phosphonate Analogs for the Treatment of Adenoviral Infection

    Amount: $599,360.00

    DESCRIPTION (provided by applicant): Adenovirus can be a significant health risk for immune-compromised patients, both adult and pediatric patients. In pediatric patients in particular, complications ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. Nucleoside Phosphonate Analogs for the Treatment of Adenoviral Infection

    Amount: $599,360.00

    DESCRIPTION provided by applicant Adenovirus can be a significant health risk for immune compromised patients both adult and pediatric patients In pediatric patients in particular complications ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of HealthDepartment of Health and Human Services
  4. Broad Spectrum Antiviral Nucleoside Phosphonate Analogs

    Amount: $597,046.00

    DESCRIPTION: The Working Group for Civilian Biodefense has identified orthopox DNA viruses such as variola as a potential bioterrorism threat, and numerous other DNA viruses, including herpes, adeno, ...

    SBIR Phase I 2013 Department of Health and Human Services
  5. Prodrugs of Neuraminidase Inhibitors for Increased Oral Bioavailability

    Amount: $2,585,246.00

    DESCRIPTION (provided by applicant): Virally-encoded neuraminidase plays a key role in the life-cycle of the influenza virus. A class of anti-influenza drugs that inhibits the action of neuraminidase ...

    SBIR Phase II 2011 Department of Health and Human Services
  6. Novel prodrugs for treatment of human CMV infection

    Amount: $591,457.00

    DESCRIPTION (provided by applicant): As a result of the widespread use of antiviral prophylaxis and pre-emptive therapy, the incidence and severity of human cytomegalovirus (HCMV) disease and its indi ...

    SBIR Phase I 2010 Department of Health and Human Services
  7. Development of the orally delivered, non-absorbable ACE inhibitor enalaprilat for

    Amount: $197,747.00

    DESCRIPTION (provided by applicant): A major limitation with most current medical therapies for inflammatory bowel disease (IBD) is the indiscriminant immunosuppressive effect of these drugs. We have ...

    SBIR Phase I 2010 Department of Health and Human Services
  8. Development of orally delivered, non-absorbable AT1 receptor antagonists for infl

    Amount: $268,620.00

    DESCRIPTION (provided by applicant): A major limitation with most current medical therapies for inflammatory bowel disease (IBD) is the indiscriminant immunosuppressive effect of these drugs. We have ...

    SBIR Phase I 2009 Department of Health and Human Services
  9. Prodrugs of Neuraminidase Inhibitors for Increased Oral Bioavailability

    Amount: $185,621.00

    DESCRIPTION (provided by applicant): Virally-encoded neuraminidase plays a key role in the life-cycle of the influenza virus. A class of anti-influenza drugs that inhibits the action of neuraminidase ...

    SBIR Phase I 2009 Department of Health and Human Services
  10. Bile acid conjugates for improving the oral bioavailability of bisphosphonates

    Amount: $255,852.00

    DESCRIPTION (provided by applicant): Bisphosphonates are chemically and enzymatically stable analogues of inorganic pyrophosphate that interfere with specific biochemical and enzymatic pathways of the ...

    SBIR Phase I 2008 Department of Health and Human Services

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