TSRL, INC.

Company Information

Company Name
TSRL, INC.
Address
540 AVIS DR STE A
ANN ARBOR, MI, 48108-7906
Phone
n/a
URL
n/a
DUNS
156551699
Number of Employees
n/a
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N

Award Totals

PROGRAM/PHASE
AWARD AMOUNT ($)
NUMBER OF AWARDS
SBIR Phase I
$6,075,545.00
25
SBIR Phase II
$8,600,232.00
7

Award List

  1. Novel prodrugs for treatment of human CMV infection

    Amount: $591,457.00

    DESCRIPTION (provided by applicant): As a result of the widespread use of antiviral prophylaxis and pre-emptive therapy, the incidence and severity of human cytomegalovirus (HCMV) disease and its indi ...

    SBIR Phase I 2010 Department of Health and Human Services
  2. Development of the orally delivered, non-absorbable ACE inhibitor enalaprilat for

    Amount: $197,747.00

    DESCRIPTION (provided by applicant): A major limitation with most current medical therapies for inflammatory bowel disease (IBD) is the indiscriminant immunosuppressive effect of these drugs. We have ...

    SBIR Phase I 2010 Department of Health and Human Services
  3. TECHNOLOGY FOR ORAL DELIVERY OF FIRST-PASS DRUGS

    Amount: $47,000.00

    STRATEGIES FOR REDUCING THE DOSING INTERVAL OF ORALLY ABSORBED DRUGS RELY ON CHANGING THE RELEASE PATTERN OF THE DRUG FROM THE DELIVERY SYSTEM SO THAT THE BLOOD LEVEL PROFILE OF THE DRUG FALLS WITHIN ...

    SBIR Phase I 1987 Department of Health and Human Services
  4. POSITION-SENSITIVE SCINTILLATION FLOW COUNTER

    Amount: $456,131.00

    A NOVEL PRINCIPLE FOR SIMULTANEOUS SCINTILLATION COUNTING OF MULTIPLE RADIOACTIVE SAMPLES IS PROPOSED. THE IMMEDIATE GOAL OF THIS PROPOSAL IS TO CONSTRUCT AND TEST A SIX-SAMPLE PROTOTYPE DEVICE TO PRO ...

    SBIR Phase II 1992 Department of Health and Human Services
  5. TOPICAL DELIVERY OF LIPOSOMALLY ENCAPSULATED INTERFERON

    Amount: $484,173.00

    ABOUT FIVE MILLION AMERICANS SUFFER FROM GENITAL HERPES, WITH AN ESTIMATED ONE-HALF MILLION INDIVIDUALS HAVING BECOME INFECTED IN 1981 ALONE. ALTHOUGH MANY FORMS OF THERAPY HAVE BEEN TESTED, NONE HAS ...

    SBIR Phase II 1993 Department of Health and Human Services
  6. TECHNOLOGY FOR IMPROVED ORAL DELIVERY OF ANTI-HIV DRUGS

    Amount: $50,000.00

    THE LONG-TERM OBJECTIVE IS TO DEVELOP AN ORAL DRUG DELIVERY STRATEGY AND TECHNOLOGY BASE TO INCREASE THE EXTENT OF ABSORPTION AND DECREASE THE VARIABILITY OF THE ABSORPTION OF NUCLEOTIDE ANTIVIRAL DRU ...

    SBIR Phase I 1992 Department of Health and Human Services
  7. Targeted Delivery of Recombinant Adenovirus to Gut

    Amount: $81,000.00

    Inflammatory bowel disease (IBD) is a collective term that includes Crohn's disease andulcerative colitis. Although both disorders have a distinct clinical course with characteristicpathophysiology, t ...

    SBIR Phase I 1994 Department of Health and Human Services
  8. "Protected" Nanoparticles for an Oral Single-Dose Staphylocaccal Enterotoxin B Vaccine

    Amount: $69,902.00

    Conventional methods of immunization in general require multiple injections at certain intervals to achieve the required protective immune response. However, this immunization protocol may not always ...

    SBIR Phase I 1995 ArmyDepartment of Defense
  9. Adenoviral Mediated Gene Therapy for Experimental Glioma

    Amount: $632,576.00

    Gliomas are the most common primary intracranial brain tumors and are thought to arise as a neoplastransformation of glial cells in the central nervous system. The prognosis for the disease is poor.su ...

    SBIR Phase II 1997 Department of Health and Human Services
  10. ORAL DELIVERY OF ENCAPSULATED MULTIMERIC AIDS VACCINES

    Amount: $155,244.00

    Not Available This Phase I SBIR proposal is aimed at developing a design capability and comprehensive set of simulation tools for exploring the feasibility and making a realistic assessment of the po ...

    SBIR Phase I 1999 Department of Health and Human Services

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