ORAL DELIVERY OF ENCAPSULATED MULTIMERIC AIDS VACCINES

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$155,244.00
Award Year:
1999
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Agency Tracking Number:
1R43AI044532-01
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
TSRL, INC.
540 AVIS DR, STE A, ANN ARBOR, MI, 48108
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
JOHN HILFINGER
() -
Business Contact:
(734) 663-4233
JCRISON@PORTSYSTEMS.COM
Research Institution:
n/a
Abstract
Not Available This Phase I SBIR proposal is aimed at developing a design capability and comprehensive set of simulation tools for exploring the feasibility and making a realistic assessment of the potential for advanced rocket propulsion based on the Pulsed Detonation Engine (PDE) cycle. The PDE is a new engine concept that provides higher specific impulse than conventional rockets because of its constant-volume, nonsteady operating cycle. It also has several advantages because of its simple design. In PDEs a detonation wave initiated in a fuel-oxidizer mixture propagates exially in the detonation chamber, producing thrust when it loads the thrust wall. In Phase I we will identify the codes needed for modeling PDE operation and benchmark them against a previously developed prototype engine. In Phase II we will calibrate and test them in connection with all the key PDE processes: injection, mixing, detonation initiation, evolution, and propagation, venting of exhaust products, and the acoustic signature and structural response of a multiple-chamber PDE, thus enabling realistic end-to-end PDE performance simulation. Using these tools we will design and build a flight-capable full-scale propulsion system.

* information listed above is at the time of submission.

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