EVALUATION OF RETROVENOUS MYOCARDIAL DRUG DELIVERY SYSTEM

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$484,000.00
Award Year:
1988
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Agency Tracking Number:
4973
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Ubtl Inc.
520 Wakara Way, Salt Lake City, UT, 84108
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Jeffrey L Peters
Principal Investigator
(801) 584-3232
Business Contact:
() -
Research Institution:
n/a
Abstract
THE FEASIBILITY OF RETROVENOUS MYOCARDIAL DRUG DELIVERY (XYLOCAINE) TO TREAT AND CONTROL ARRHYTHMIAS WILL BE TESTED IN SHEEP AFTER CORONARY ARTERY OCCULSION, AND THEN COMPARED TO THE STANDARD INTRAVENOUS ROUTE. ENDPOINTS OF NUMBER AND TYPE OF ARRHYTHMIAS, XYLOCAINE DOSE, PLASMA, AND MYOCARDIAL XYLOCAINE CONCENTRATIONS WILL BE DETERMINED. THE DEMONSTRA-TION OF THE HYPOTHESIS THAT RETROVENOUS MYOCARDIAL DRUG DELIVERY IS SUPERIOR TO INTRAVENOUS THERAPY AFTER CORONARY ARTERY OCCLUSION COULD PROVIDE AN EFFECTIVE METHOD FOR THE TREATMENT OF VENTRICULAR ARRHYTHMIAS.

* information listed above is at the time of submission.

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