INVITRO EPITHELIZATION OF A HOLLOW VISCUS PROSTHESIS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$47,000.00
Award Year:
1988
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
7980
Agency Tracking Number:
7980
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
520 Wakara Way, Salt Lake, UT, 84108
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
() -
Business Contact:
Richard E Hoffer
(801) 583-3600
Research Institution:
n/a
Abstract
THIS PROPOSED STUDY IS DESIGNED TO DEVELOP AND EVALUATE A METHOD OF EPITHELIZING, IN VITRO, A COMPOUND HOLLOW VISCUS PROSTHESIS CONSISTING OF AN OUTER RIGID POROUS MATERIAL AND A BIODEGRADABLE INNER LAYER. HEALING OF THE PROSTHESIS IN THE WALL OF THE URINARY BLADDERWILL BE EVALUATED IN DOGS. THE PROSTHESIS WILL BE EVALUATEDFOR URINE LEAKAGE, INFECTION, EXTRUSION, REJECTION, INCOR- PORATION INTO THE URINARY BLADDER WALL, AND CALCULUS FORMA- TION BY CYSTOGRAPHY, GROSS PATHOLOGY, AND LIGHT MICROSCOPY. THE SUCCESSFUL DEVELOPMENT OF A PROSTEHETIC URINARY TRACT WOULD HAVE EXTENSIVE COMMERCIAL APPLICABILITY EITHER AS A COMPLETE SYSTEM OR AS INDIVIDUAL COMPONENTS. A PROSTHETIC BLADDER WOULD BENEFIT TO THE MORE THAN 10,000 PATIENTS REQUIRING CYSTECTOMY ANNUALLY.

* information listed above is at the time of submission.

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