Nanosensor Cartridge for Bioagent Detection within Geospatial Networked Motes

Award Information
Agency: Department of Defense
Branch: Army
Contract: W912HZ-09-C-0046
Agency Tracking Number: A083-169-0075
Amount: $119,954.00
Phase: Phase I
Program: SBIR
Awards Year: 2009
Solicitation Year: 2008
Solicitation Topic Code: A08-169
Solicitation Number: 2008.3
Small Business Information
4401 Dayton-Xenia Road, Dayton, OH, 45432
DUNS: 074689217
HUBZone Owned: N
Woman Owned: Y
Socially and Economically Disadvantaged: N
Principal Investigator
 Melanie Tomczak
 Research Scientist
 (937) 426-6900
Business Contact
 Bryce Skinn
Title: Business Relations Manager
Phone: (937) 426-6900
Research Institution
Detection of biological warfare agents in a real-world setting is an increasingly urgent problem. Many of the current state-of-the-art sensors are aqueous based and require large biomolecules, such as antibodies, to achieve binding of the target molecule and subsequent reporting of the binding event. These technical hurdles are a drawback when considering deployment of these technologies to a battlefield situation. Here, we propose a sensor that is based on short peptide sequences that act as ligands for the target(s) of interest. Due to their small size, these ligands are not susceptible to conformational instability and the sensors should have a long lifetime even when deployed. Additionally, the sensor incorporates an exponential amplification of the output signal when the target of interest binds, effectively eliminating the background and false positive results.

* Information listed above is at the time of submission. *

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