Nanosensor Cartridge for Bioagent Detection within Geospatial Networked Motes

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$119,954.00
Award Year:
2009
Program:
SBIR
Phase:
Phase I
Contract:
W912HZ-09-C-0046
Agency Tracking Number:
A083-169-0075
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
UES, INC.
4401 Dayton-Xenia Road, Dayton, OH, 45432
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
074689217
Principal Investigator:
Melanie Tomczak
Research Scientist
(937) 426-6900
mtomczak@ues.com
Business Contact:
Bryce Skinn
Business Relations Manager
(937) 426-6900
bskinn@ues.com
Research Institution:
n/a
Abstract
Detection of biological warfare agents in a real-world setting is an increasingly urgent problem. Many of the current state-of-the-art sensors are aqueous based and require large biomolecules, such as antibodies, to achieve binding of the target molecule and subsequent reporting of the binding event. These technical hurdles are a drawback when considering deployment of these technologies to a battlefield situation. Here, we propose a sensor that is based on short peptide sequences that act as ligands for the target(s) of interest. Due to their small size, these ligands are not susceptible to conformational instability and the sensors should have a long lifetime even when deployed. Additionally, the sensor incorporates an exponential amplification of the output signal when the target of interest binds, effectively eliminating the background and false positive results.

* information listed above is at the time of submission.

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