A TOTALLY SPECIFIC, HIGHLY SENSITIVE, RAPID RESPONDING, ACCURATE, AND REPRODUCIBLE PHOSPHATE ELECTRODE PROBE WILL BEDEVELOPED.

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 4718
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Awards Year: 1986
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Universal Sensors
5258 Veterans Memorial Blvd, Suite D, Metairie, LA, 70006
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 DR GEORGE G GUILBAULT
 PRINCIPAL INVESTIGATOR
 (504) 885-8443
Business Contact
Phone: () -
Research Institution
N/A
Abstract
A TOTALLY SPECIFIC, HIGHLY SENSITIVE, RAPID RESPONDING, ACCURATE, AND REPRODUCIBLE PHOSPHATE ELECTRODE PROBE WILL BEDEVELOPED. IT WILL BE BASED ON THE USE OF ENZYME SYSTEMS. THE ENZYMES ACID OR ALKALINE PHOSPHATASE AND GLUCOSE OXIDASEWILL BE COIMMOBILIZED ONTO AN OXYGEN OR PEROXIDE SENSOR; THIS WILL CONSTITUTE THE PHOSPHATE PROBE. A VARIATION OF EITHER OF THESE TWO SPECIES, DUE TO THE ENZYMATIC REACTIONS:GLUCOSE+O2+GLUCOSE OXIDASE-H2O2+GLUCONIC ACID PHOSPHATE+GLUCOSE+PHOSPHATASE-GLUCOSE-PHOSPHATE WILL BE PROPORTIONAL TO THE PHOSPHATE CONCENTRATION. THE ELECTRODE CONFIGURATION WILL BE OPTIMIZED TO GIVE A LONG LIFETIME, HIGH SELECTIVITY, GOOD ACCURACY AND REPRODUCIBILITY, AND SENSITIVITY. IT WILL BE CAPABLE OF OPERATION BOTH IN VIVO AND IN VITRO.

* information listed above is at the time of submission.

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