DECISION SUPPORT FOR HIV SCREENING IN BLOOD BANKS

Award Information
Agency:
Department of Health and Human Services
Amount:
$441,446.00
Program:
SBIR
Contract:
N/A
Solitcitation Year:
N/A
Solicitation Number:
N/A
Branch:
N/A
Award Year:
1992
Phase:
Phase II
Agency Tracking Number:
13654
Solicitation Topic Code:
N/A
Small Business Information
University Park Pathology Assc
1408 W University Ave, Urbana, IL, 61801
Hubzone Owned:
N
Woman Owned:
N
Socially and Economically Disadvantaged:
N
Duns:
N/A
Principal Investigator
 Harriet H Imrey
 (217) 367-3645
Business Contact
Phone: () -
Research Institution
N/A
Abstract
OPTIMAL DESIGN OF PROCEDURES AND PROTOCOLS FOR SCREENING BLOOD AND BLOOD PRODUCTS FOR HUMAN IMMUNODEFICIENCY VIRUS (HIV) IS DEPENDENT ON CONSIDERATION OF SEROPREVALENCE IN THEDONOR POPULATION (ACKNOWLEDGING THAT THERE ARE SIGNIFICANT REGIONAL DIFFERENCES), ON THE PREVALENCE OF AND OVERLAP WITHOTHER MARKERS SUCH AS THOSE FOR HEPATITIS, AND ON VOLUNTARY SELF-DEFERRAL BEHAVIOR UNDER DIFFERENT CONTINGENCIES. THIS PROJECT WILL EXPLORE THE FEASIBILITY OF INCORPORATING THESE VARIABLES AND THEIR INTERACTIONS INTO A COMPUTER-BASEDDECISION SUPPORT PACKAGE FOR THE BLOOD BANKING COMMUNITY IN ORDER TO ASSIST IN THE ESTIMATION OF THE ECONOMIC, LEGAL, AND POLICY CONSEQUENCES OF CURRENT VS. ALTERNATIVE SCREENING PROTOCOLS FOR HIV IN DONATED BLOOD. IN ADDITION, SUCH ALTERNATIVE PROTOCOLS ARE TO BE ORIENTED TO EVEN FURTHER INCREASING THE SAFETY OF THE BLOOD SUPPLY WHILE MINIMIZING DONOR ATTRITION. IF THE PARAMETERS FOR A DECISION-PROMPTING MODEL TO SIMULATETHE EFFECTS OF ALTERNATIVE SCREENING PROCEDURES CAN BE IDENTIFIED AND DOCUMENTED DURING PHASE I, A PHASE II VENTURE FOR THE DEVELOPMENT OF AN APPROPRIATE SOFTWARE PACKAGE IS PLANNED.

* information listed above is at the time of submission.

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