THE USE OF A ONE STEP IMMUNOASSAY FOR DETECTING INFECTIOUS/TOXIC AGENTS

Award Information
Agency: Department of Defense
Branch: Army
Contract: N/A
Agency Tracking Number: 6609
Amount: $48,226.00
Phase: Phase I
Program: SBIR
Awards Year: 1987
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Vanguard Research Labs Inc
36 S Chester, Pasadena, CA, 91106
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 DONALD E ROUNDS
 (818) 795-4343
Business Contact
Phone: () -
Research Institution
N/A
Abstract
A RECENTLY DEVELOPED ONE STEP IMMUNOLOGICAL ASSAY SYSTEM IS BEING PROPOSED TO ADDRESS THE NEED FOR A RAPID METHOD FOR IDENTIFYING INFECTIOUS AGENTS THAT HAVE MILITARY IMPORTANCE. THE TEST SYSTEM CONSISTS OF A DIPSTICK AND A SEALED ENVELOPE CONTAINING LYOPHILIZED PRECOLORED REACTANTS. THE REACTANTS CONSIST OF MOLECULAR COMPLEXERS OF ANTIBODY MOLECULES WHICH ARE PREAMPLIFIED WITH COLORED AVIDIN/BIOTIN RESIDUES. THE TEST IS PERFORMED BY THE ADDITION OF TWO DROPS OF THE TEST SOLUTION, TO SOLUBILIZE THE REACTANTS AND PERMIT INTERACTION FO THE ANTIBODIES WITH THE ANTIGEN MOLECULES, IF PRESENT. COLOR IS DEPOSITED ON THE MEMBRANE OF THE INSERTED DIPSTICK TO FORM EITHER A PLUS OR MINUS SIGN DURING AN INITIAL 15 MINUTE INCUBATION PERIOD, TO INDICATE THE PRESENCE OR ABSENCE OF THE ANTIGEN. THE TEST SYSTEM IS PORTABLE, ECONOMICAL, EASY TO USE AND SENSITIVE TO LESS THAN A NANOGRAM OF ANTIGEN.

* information listed above is at the time of submission.

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government