SIGNAL-BASED ANALYSIS OF CLINICAL MICROBIOLOGY

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$0.00
Award Year:
2002
Program:
SBIR
Phase:
Phase I
Contract:
2R44AI048332-02
Award Id:
60439
Agency Tracking Number:
AI048332
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
VECNA TECHNOLOGIES, INC., 6525 BELCREST ROAD, STE 612, HYATTSVILLE, MD, 20782
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
DANIELTHEOBALD
(301) 864-7253
THEO@VECNA.COM
Business Contact:
DANIELTHEOBALD
(301) 864-7253
THEO@VECNA.COM
Research Institute:
n/a
Abstract
Hospital infections and antimicrobial resistance are scourges of modern society, affecting several million Americans annually and wasting billions of dollars. Timely, accurate data analysis is critical to preventing the spread of infection and resistance. Preliminary results show that treating clinical microbiology data as signals and applying various analytical techniques to them has tremendous potential to improve the detection of outbreaks and shifts in resistance early on, while the possibility for effective intervention still exists. Building on these results, this research aims to fully characterize at least five years of historical microbiology data from three prominent hospitals. This will be used as training data to optimize early detection techniques through the use of genetic algorithms (GAs) using a Linux supercomputing cluster. Surveys will be conducted of the infection control personnel before and after a one year trial of an early prototype real-time monitoring system to determine the impact such a system has on their ability to prevent the spread of infectious disease. Success will be measured by the survey results as well as by the number of outbreaks detected in a timely manner. This research will extend the scientific understanding of GAs, infectious disease surveillance, and cluster detection.

* information listed above is at the time of submission.

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