Surface Selective Chiral Detector

Award Information
Agency: Department of Commerce
Branch: N/A
Contract: SB1341-02-W-1118
Agency Tracking Number: 7.04.01
Amount: $75,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2002
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
737 4th Street, Lyons, CO, 80540
DUNS: 112697136
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Scott Davis
 VP Technology
 (303) 823-9229
Business Contact
 Mike Anderson
Title: President
Phone: () -
Research Institution
A novel approach to the problem of surface-selective chiral detection is presented. In a small and potentially inexpensive optical package, chiral molecules adsorbed to the surface of a guided wave optic are probed via the evanescent field of the guided radiation. Single-mode guided-wave optics are exploited to increases the analyte-probe interaction region compared to traditional methods such as attenuated total-reflectance spectroscopy. Techniques for both circular-dichroism and optical-rotary-dispersion measurements will be studied and compared. In Phase 1 surface selectivity will be demonstrated in an optical-breadboard experiment. In Phase 2 a prototype of a surface-selective chiral spectrometer will be developed. This device promises to be useful in the characterization and understanding of the increasingly important field of chiral stationary phases as it relates to HPLC and enantio-specific synthesis.

* Information listed above is at the time of submission. *

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