Surface Selective Chiral Detection: A New Metrology Technique

Award Information
Agency: Department of Commerce
Branch: National Institute of Standards and Technology
Contract: N/A
Agency Tracking Number: 400-5
Amount: $300,000.00
Phase: Phase II
Program: SBIR
Awards Year: 2003
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
2927 Welton Street, Denver, CO, 80205
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Scott Davis
 () -
Business Contact
Phone: () -
Research Institution
The near chiral purity of the biosphere leads to a vast array of chiro-specific physiological responses. This chiro-specificity, in turn, gives rise to the need for the manufacturing of enantiomerically pure chiral chemicals, such as pesticides, pharmaceuticals, food additives, pigments, etc. Critical to the efficacy of both chiro-specific biology and chiro-synthesis/separation are the interfacial regions of chiral surface layers. Vescent Photonics proposes to develop an entirely new metrology technique designed to investigate chiral surface layers. The technique combines the established fields of optical activity (circular dichroism and optical rotary dispersion) for chiro-specificity with evanescent wave sensing for surface selectivity. The device employs a new polarization modulator, with demonstrated speeds of greater than 200 kHz and great potential for compact, and economic construction.

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