THE LONG-TERM OBJECTIVES OF THE PROPOSED RESEARCH ARE TO FURTHER DEVELOP THE DIFFERENTIAL VISCOMETER (DV) AND TO DEMONSTRATE THE POTENTIAL UTILITY OF THIS NEW INSTRUMENT FOR THE SOLUTION OF SIGNIFICANT BIOMEDICAL PROBLEM SPECIFICALLY IN PHASE I IT IS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$48,500.00
Award Year:
1984
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Award Id:
1501
Agency Tracking Number:
1501
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
1030 Russell Drive, Porter, TX, 77365
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
M.A. HANEY
PRESIDENT
() -
Business Contact:
() -
Research Institute:
n/a
Abstract
THE LONG-TERM OBJECTIVES OF THE PROPOSED RESEARCH ARE TO FURTHER DEVELOP THE DIFFERENTIAL VISCOMETER (DV) AND TO DEMONSTRATE THE POTENTIAL UTILITY OF THIS NEW INSTRUMENT FOR THE SOLUTION OF SIGNIFICANT BIOMEDICAL PROBLEM SPECIFICALLY IN PHASE I IT IS INTENDED TO ACCOMPLISH THE FOLLOWING: (1) SHOW THAT THE SPEED AND SENSITIVITY OF THE DV MAKES IT USEFUL IN A SCREENING PROGRAM TO DETECT DRUGS AND OTHER COMPOUNDS THAT INTERCALATE WITH DNA. (2) COUPLE A SIMPLE FLOW INJECTION ANALYSIS SYSTEM TO THE DV FOR AN ALTERNATIVE APPROACH TO THE DNA-DRUG TESTING. (3) DEVELOP A MODIFIED DV FOR USE AS AN ON-LINE DETECTOR FOR GPC/HPLC. THESE GOALS HAVE CONSIDERABLE POTENTIAL FOR PRODUCING A LINE OF COMMERCIAL INSTRUMENTS THAT INTERFACE WITH A WIDE RANGE OF TECHNIQUES IN BIOCHEMISTRY. PARTICULAR NEEDS EXPRESSED IN THE SBIR SOLICITATION THAT RELATE TO THE PRESENT WORK INCLUDE: NATIONAL CANCER INSTITUTE: CANCER TREATMENT, ITEMS B(5), C(2), C(4). NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES; CHARACTERIZATION OF ENVIRONMENTAL AGENTS, ITEM C, BIOLOGICAL RESPONSE TO ENVIRONMENTAL AGENTS, ITEM B, TEST DEVELOPMENT, ITEM A. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES; PHARMACOLOGICAL SCIENCES, ITEM F, PHYSIOLOGY AND BIOMEDICAL ENGR., ITEM B.

* information listed above is at the time of submission.

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