INFRARED FLUORESCENT GASTROINTESTINAL ENDOSCOPY

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$50,000.00
Award Year:
1992
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Agency Tracking Number:
19199
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Western Research Company Inc
2127 East Speedway, Tucson, AZ, 85719
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Brian L Craine
(602) 325-4505
Business Contact:
() -
Research Institution:
n/a
Abstract
THE PHASE I RESEARCH PROJECT WILL BE A SERIES OF PROOF-OF-PRINCIPLE EXPERIMENTS DESIGNED TO SHOW THE FEASIBILITY OF USING INFRARED FLORESCENCE TO DETECT BLOOD FLOW IN THE SUBMUCOSA OF THE HUMAN GUT. THIS WILL BE ACCOMPLISHED BY RETROFITTING A SIGMOIDOSCOPE FOR IMAGING IN THE NEAR IR. THE SENSITIVITY OF THIS SYSTEM TO DETECT FLORESCENCE FROM THE DYE INDOCYANINE GREEN INDUCED BY IRRADIATION WITH A NEAR IR LASER DIODE WILL BE DETERMINED. THE EFFECTIVE DEPTH OF TISSUE THROUGH WHICH SUCH A SYSTEM CAN IMAGE WILL BE DETERMINED. THE COMPLETION OF THESE STUDIES WILL PROVIDE THE NECESSARY INFORMATION TO DETERMINE THE EFFICACY OF THIS TYPE OF IMAGING SYSTEM. A POSITIVE RESULT WOULD SUGGEST THAT THIS SYSTEM COULD BE MORE SENSITIVE AND MORE COST EFFECTIVE THAN THE PRESENTLY USED FLUORESCEIN FLU0RESCENT FLOWMETRY.

* information listed above is at the time of submission.

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