NEW HPLC SUPPORTS FOR BIOCHEMICAL PURIFICATIONS

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$47,625.00
Award Year:
1992
Program:
SBIR
Phase:
Phase I
Contract:
n/a
Agency Tracking Number:
19248
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
Wilhelmy Fine Particles
136 Summit Street, West Lechburg, PA, 15656
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Richard B Wilhelmy
(412) 845-6238
Business Contact:
() -
Research Institution:
n/a
Abstract
NEW HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC (HPLC) SUPPORTS WILL BE DEVELOPED THAT CAN SIGNIFICANTLY LOWER THE DOWNSTREAM PROCESSING COSTS OF BIOLOGICALLY SIGNIFICANT PRODUCTS SUCH AS ANTIBODIES, VACCINES, AND DRUGS. THE NEW SUPPORTS WILL BE SYNTHESIZED BY COATING THE COMPANY'S PROPRIETARY CALCIUM PHOSPHATE PARTICLES WITH THIN POLYMER LAYERS. THE COMBINATION OF POLYMER COATINGS WITH THE UNIQUE PARTICLE MORPHOLOGY ARE EXPECTED TO PROVIDE THE FOLLOWING ADVANTAGES SIMULTANEOUSLY: RIGIDITY, NON SWELLING, HIGH PRODUCTIVITY, HIGH PERFORMANCE, LINEAR SCALE-UP, LOW PRESSURE DROP, LOW NON-SPECIFIC ADSORPTION, BIOCOMPATIBILITY, AND LOW BLEEDING OF BONDED PHASES.

* information listed above is at the time of submission.

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