DEVELOPMENT OF A SIMPLE QUANTITATIVE TEST FOR CHOLINESTERASE ACTIVITY

Award Information
Agency: Department of Defense
Branch: Army
Contract: N/A
Agency Tracking Number: 6658
Amount: $51,739.00
Phase: Phase I
Program: SBIR
Awards Year: 1987
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
Zoion Research Inc
214 Lincoln St, Allston, MA, 02134
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 DR ROBERT BURROWS
 (617) 782-5713
Business Contact
Phone: () -
Research Institution
N/A
Abstract
WE PLAN TO ADAPT A LABORATORY ASSAY FOR ACETYLCHOLINESTERASE ACTIVITY FOR USE AS A TEST STRIP FOR CHOLINESTERASE ACTIVITY IN SALIVA AND SMALL AMOUNTS OF SERUM. WE ANTICIPATE THAT THIS TEST STRIP WILL BE SIMPLE TO USE AND NOT REQUIRE SPECIAL EQUIPMENT, AND WILL YIELD QUANTITATIVE RESULTS WITH ENZYME ON THE ORDER OF 250 UU. PHASE I EFFORT WILL BE DIRECTED TOWARDS PREPARING THE TEST STRIPS AND VALIDATING THE ASSAY WITH PURIFIED ENZYMES AND FLUID SAMPLES FROM NORMAL INDIVIDUALS.

* information listed above is at the time of submission.

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