Bioimpedance Control of Ultrafiltration on Hemodialysis

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$100,000.00
Award Year:
1995
Program:
SBIR
Phase:
Phase I
Contract:
1 R43 DK49892-01,
Award Id:
29393
Agency Tracking Number:
29393
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
2701-B Kent Avenue, West Lafayette, IN, 47906
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
n/a
Principal Investigator:
Stephen Ash
() -
Business Contact:
() -
Research Institute:
n/a
Abstract
We will apply thoracic electric bioimpedance monitoring by external electrodes (TEB) to those patieunstable on hemodialysis and find a primary cardiovascular parameter which predicts the onset of symOur expectation is that percent fall in cardiac output will be the primary indicator, but we will alcardiovascular parameters, machine-generated ultrafiltration data, and SO2 and hematocrit (by Crit-Lthat there are no better predictors of symptomatic hypotension. We will define a "stop-UF" algorithmultrafiltration rate before symptomatic hypotension and clinically test this in Phase II. Also in Phclinically test a "dry weight" algorithm which monitors cardiovascular parameters and receives usersymptoms and clinical findings to automatically determine dry weight of all hemodialysis patients.

* information listed above is at the time of submission.

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