Deployable Intracranial Sensor Array

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$99,972.00
Award Year:
2006
Program:
STTR
Phase:
Phase I
Contract:
W81XWH-06-C-0400
Agency Tracking Number:
A064-028-0170
Solicitation Year:
2006
Solicitation Topic Code:
A06-T028
Solicitation Number:
n/a
Small Business Information
INFOSCITEX CORPORATION
303 Bear Hill Road, Waltham, MA, 02451
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
004627316
Principal Investigator:
Anna Galea
(781) 890-1339
agalea@infoscitex.com
Business Contact:
William Thompson
Contracts Official
(781) 890-1338
bthompson@infoscitex.com
Research Institution:
CHILDREN'S HOSPITAL BOSTON
Norman Dean
300 Longwood Ave
Boston, MA, 02115
(617) 355-6005
Domestic nonprofit research organization
Abstract
Cortical Spreading Depression (CSD) as a secondary phenomenon to traumatic head injury can herald further brain tissue damage well after the initial injury. The only way to reliably record CSD is through direct electrode contact with the brain. With modern equipment this requires that the skull and dura be removed, which is only feasible in a small number of patients. Infoscitex and our partners at Children’s Hospital Boston propose a novel subdural electrode array capable of being inserted through a standard hole used for intra-cranial pressure (ICP) monitoring. One of our arrays alone can cover 6 cm2 of cortical tissue, and has electrodes spaced up to 1 cm apart. The design of our array is ideal for recording the low-frequency waves of CSD. Our array will be beneficial in cases both of traumatic head injury and also brain injuries from stroke. The potential benefits to monitoring for CSD in all patients who require ICP monitoring is vast, due to the number of potential patients and the high incidence of secondary injury. The team assembled for this program involves experts in the field of subdural electrode placement and signal recording, as well as considerable experience in developing minimally invasive medical devices.

* information listed above is at the time of submission.

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