Non-invasive monitoring of intracranial pressure

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-07-C-0011
Agency Tracking Number: A062-151-2161
Amount: $69,986.00
Phase: Phase I
Program: SBIR
Awards Year: 2006
Solicitation Year: 2006
Solicitation Topic Code: A06-151
Solicitation Number: 2006.2
Small Business Information
303 Bear Hill Road, Waltham, MA, 02451
DUNS: 004627316
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Anna Galea
 Biomedical Systems Manager
 (781) 890-1338
Business Contact
 William Thompson
Title: Contracts Manager
Phone: (781) 890-1338
Research Institution
Intracranial pressure, ICP, is arguably the single most important parameter used clinically to manage brain injury and long-term brain damage. Existing methods to record ICP are invasive, however, either going through the skull or into a brain ventricle. Many researchers are currently exploring methods for monitoring ICP through non-invasive means. Our work combines two highly promising methods, both backed by clinical research performed by our teaming partners, and combine them into a single device that will lead to the definitive non-invasive device for monitoring ICP in far-field use. Our device incorporates ophthalmodynamometry and arterial phase lag monitoring into a single, compact unit safe for continuous automated use. We present innovations in ophthalmodynamometry that enable this leap to continuous use as well as image analysis that can rapidly analyze the retinal images and data integration to provide feedback from multiple sensors. Our device will enable monitoring of ICP on all patients with suspected brain injury, which will benefit the military as well as civilian health providers, from EMTs and paramedics to nurses and doctors in central hospitals.

* Information listed above is at the time of submission. *

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