Rapid Isolation of DNA Aptamers (RIDA)

Award Information
Agency: Department of Defense
Branch: Air Force
Contract: FA8650-07-M-6831
Agency Tracking Number: F071-045-0255
Amount: $99,934.00
Phase: Phase I
Program: SBIR
Awards Year: 2007
Solitcitation Year: 2007
Solitcitation Topic Code: AF071-045
Solitcitation Number: 2007.1
Small Business Information
INFOSCITEX CORP.
303 Bear Hill Road, Waltham, MA, 02451
Duns: 004627316
Hubzone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Vladimir Gilman
 Senior Engineer
 (781) 890-1338
 vgilman@infoscitex.com
Business Contact
 William Thompson
Title: Contracts Manager
Phone: (781) 890-1338
Email: bthompson@infoscitex.com
Research Institution
N/A
Abstract
DNA aptamers are promising highly-specific, environmentally-stable threat-detecting molecules. Unfortunately, the current method for generating these materials yields a product frought with a high concentration of ballast aptamers. A laborious, yet automated process is required to isolate the desired molecules, thereby precluding their widespread use. Infoscitex (IST) proposes to develop a rapid aptamer production process that relies upon the law of mass action to make selection of high affinity and selective aptamers after only one round. The Phase I program will focus on demonstrating the approach to be rapid, scalable, and economical. Upon successful completion of Phase I, Phase II/III activities will focus on the continued development and scale-up of the novel technology of aptamer isolation process.

* information listed above is at the time of submission.

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