Rapid Isolation of DNA Aptamers (RIDA)

Award Information
Agency:
Department of Defense
Branch:
Air Force
Amount:
$99,934.00
Award Year:
2007
Program:
SBIR
Phase:
Phase I
Contract:
FA8650-07-M-6831
Agency Tracking Number:
F071-045-0255
Solicitation Year:
2007
Solicitation Topic Code:
AF071-045
Solicitation Number:
2007.1
Small Business Information
INFOSCITEX CORP.
303 Bear Hill Road, Waltham, MA, 02451
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
004627316
Principal Investigator
 Vladimir Gilman
 Senior Engineer
 (781) 890-1338
 vgilman@infoscitex.com
Business Contact
 William Thompson
Title: Contracts Manager
Phone: (781) 890-1338
Email: bthompson@infoscitex.com
Research Institution
N/A
Abstract
DNA aptamers are promising highly-specific, environmentally-stable threat-detecting molecules. Unfortunately, the current method for generating these materials yields a product frought with a high concentration of ballast aptamers. A laborious, yet automated process is required to isolate the desired molecules, thereby precluding their widespread use. Infoscitex (IST) proposes to develop a rapid aptamer production process that relies upon the law of mass action to make selection of high affinity and selective aptamers after only one round. The Phase I program will focus on demonstrating the approach to be rapid, scalable, and economical. Upon successful completion of Phase I, Phase II/III activities will focus on the continued development and scale-up of the novel technology of aptamer isolation process.

* information listed above is at the time of submission.

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