Photochemical Tissue Bonding for Military Medical Applications

Award Information
Agency: Department of Defense
Branch: Air Force
Contract: FA9550-07-C-0104
Agency Tracking Number: F074-033-0333
Amount: $99,982.00
Phase: Phase I
Program: STTR
Awards Year: 2007
Solicitation Year: 2007
Solicitation Topic Code: AF07-T033
Solicitation Number: N/A
Small Business Information
303 Bear Hill Road, Waltham, MA, 02451
DUNS: 004627316
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Heather Kauth
 Project Engineer
 (781) 890-1338
 hkauth@infoscitex.com
Business Contact
 William Thompson
Title: Contracts Manager
Phone: (781) 890-1338
Email: bthompson@infoscitex.com
Research Institution
 WELLMAN CENTER FOR PHOTOMEDICINE
 Kris Betris
 40 Blossom St.
Boston, MA, 2114
 (617) 954-9353
 Domestic nonprofit research organization
Abstract
Nearly 27,000 soldiers have been injured in the present conflicts in Iraq and Afghanistan. Advances in trauma treatments have allowed a greater percentage of these casualties to survive than previously; with the advent of excellent body armor more injuries are now seen in extremities than before, including nerve and blood vessel damage. A rapid repair of vascular injuries improves outcomes for injured soldiers, by decreasing the necessity of amputation. Photochemical Tissue Bonding is a technique that consists of a photo-active dye capable of crosslinking collagen at the site of injury when exposed to an intense light source. Developed by Drs. Redmond and Kochevar of the Wellman Laboratories of Photomedicine, the technique shows exceptional promise for complete vascular repair. A system comprising a stent and light source, which will address the requirements of rapid deployment in a forward field hospital and relative simplicity of use, is required to translate this technology from the clinic to the front line. Infoscitex Corporation (IST), in cooperation with Wellman Laboratories, proposes to develop a rapidly degradable and biologically compatible stent with the appropriate mechanical properties for use in this application. Additionally IST will explore design parameters and propose solutions for a portable isotropic light source.

* Information listed above is at the time of submission. *

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