Rapid Isolation of DNA Aptamers (RIDA)

Award Information
Agency: Department of Defense
Branch: Air Force
Contract: FA8650-08-C-6867
Agency Tracking Number: F071-045-0255
Amount: $749,974.00
Phase: Phase II
Program: SBIR
Awards Year: 2008
Solicitation Year: 2007
Solicitation Topic Code: AF071-045
Solicitation Number: 2007.1
Small Business Information
303 Bear Hill Road, Waltham, MA, 02451
DUNS: 004627316
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Vladimir Gilman
 Senior Engineer
 (781) 890-1338
Business Contact
 William Thompson
Title: Contracts Manager
Phone: (781) 890-1338
Email: bthompson@infoscitex.com
Research Institution
DNA aptamers are promising highly-specific, environmentally-stable threat-detecting molecules. Unfortunately, the current method for generating these materials yields a product frought with a high concentration of ballast aptamers. A laborious, yet automated process is required to isolate the desired molecules, thereby precluding their widespread use. Infoscitex (IST) is developing a rapid aptamer production process to make selection of high affinity and selective aptamers after only one round. The ongoing Phase I program has demonstrated the approach to be rapid, scalable, and economical. The Phase II program is proposed to bring this technology to maturity and transfer to end users in the US DOD and civilian industries. The commercialization effort has been started in Phase I and will continue during the Phase II and Phase III of the program.

* Information listed above is at the time of submission. *

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