Rapid Isolation of DNA Aptamers (RIDA)

Award Information
Agency:
Department of Defense
Branch
Air Force
Amount:
$749,974.00
Award Year:
2008
Program:
SBIR
Phase:
Phase II
Contract:
FA8650-08-C-6867
Agency Tracking Number:
F071-045-0255
Solicitation Year:
n/a
Solicitation Topic Code:
n/a
Solicitation Number:
n/a
Small Business Information
INFOSCITEX CORP.
303 Bear Hill Road, Waltham, MA, 02451
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
004627316
Principal Investigator:
Vladimir Gilman
Senior Engineer
(781) 890-1338
vgilman@infoscitex.com
Business Contact:
William Thompson
Contracts Manager
(781) 890-1338
bthompson@infoscitex.com
Research Institution:
n/a
Abstract
DNA aptamers are promising highly-specific, environmentally-stable threat-detecting molecules. Unfortunately, the current method for generating these materials yields a product frought with a high concentration of ballast aptamers. A laborious, yet automated process is required to isolate the desired molecules, thereby precluding their widespread use. Infoscitex (IST) is developing a rapid aptamer production process to make selection of high affinity and selective aptamers after only one round. The ongoing Phase I program has demonstrated the approach to be rapid, scalable, and economical. The Phase II program is proposed to bring this technology to maturity and transfer to end users in the US DOD and civilian industries. The commercialization effort has been started in Phase I and will continue during the Phase II and Phase III of the program.

* information listed above is at the time of submission.

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