Non Invasive Assessment of Intracranial Pressure and Cerebrovascular Status after Traumatic Brain Injury

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-09-C-0118
Agency Tracking Number: O091-H02-3021
Amount: $99,852.00
Phase: Phase I
Program: SBIR
Awards Year: 2009
Solicitation Year: 2009
Solicitation Topic Code: OSD09-H02
Solicitation Number: 2009.1
Small Business Information
303 Bear Hill Road, Waltham, MA, 02451
DUNS: 004627316
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Anna Galea
 Principal Engineer
 (781) 890-1338
Business Contact
 Stephen Mattox
Title: Director, Finance & Contracts
Phone: (781) 890-1338
Research Institution
Intracranial pressure, ICP, is arguably the single most important parameter used clinically to manage brain injury and long-term brain damage. Existing methods to record ICP are either invasive or require large equipment incompatible with a field deployable system. Our work combines two highly promising methods for monitoring ICP into a compact unit capable of continuous monitor. Using this bimodal approach will result in a single device that will lead to the definitive non-invasive device for monitoring ICP in far-field use. Our device incorporates retinal venous doppler ultrasonography (RVD) and pressure pulsatility analysis (PPA) into a single, compact unit safe for continuous automated use. We present innovations in PPA that enable continuous monitoring with more accurate readings from the RVD. Our device will enable monitoring of ICP on all patients with suspected brain injury, which will benefit the military as well as civilian health providers, from EMTs and paramedics to nurses and doctors in central hospitals.

* Information listed above is at the time of submission. *

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