OPTIMIZATION OF KINETICS IN A NOVEL GLUCOSE SENSOR

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 2R44DK057347-02
Agency Tracking Number: DK057347
Amount: $0.00
Phase: Phase I
Program: SBIR
Awards Year: 2002
Solicitation Year: N/A
Solicitation Topic Code: N/A
Solicitation Number: N/A
Small Business Information
SENSOR TECHNOLOGIES, INC.
SENSOR TECHNOLOGIES, INC., PARK NINE WEST, SHREWSBURY, MA, 01545
DUNS: N/A
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 DAVID WOLF
 (508) 842-0432
 DEWOLF@BIOSENSORGROUP.COM
Business Contact
 JOHN HAYES
Phone: (508) 842-0432
Email: BHTJACKL@AOL.COM
Research Institution
N/A
Abstract
This Phase II SBIR involves the testing of a minimally invasive glucose sensor in vivo. Diabetes is an increasingly common lifelong disease and is associated with many complications. It is responsible for an estimated 10-15 percent of all health care expenditures. Effective treatment has been shown to prevent or delay many of the associated complications. The most common current treatments include diet, exercise, and self-monitoring of blood glucose (SMBG). An improvement to the current method would enable and encourage patients to monitor their glucose levels more closely and thus improve the general health and quality of life of the diabetic population. The technology is based on a small optical sensor implant that is fluorescent and detectable through the skin. We will finalize the sensor configuration to obtain the fastest kinetics. Animal efficacy trials must be performed to bring the sensor closer to clinical trials in humans. The performance of the sensor will be studied in vivo to demonstrate that the sensor correlates with blood glucose and follows glucose changes in tolerance tests. In vivo testing will be performed to determine the recalibration interval, the reproducibility, and the accuracy of the sensor. The lifetime and biocompatibility of the sensor will also be determined.

* information listed above is at the time of submission.

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