A Percutaneous Ultrasound-Guided Catheter for Organ and Vascular Access

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$133,446.00
Award Year:
2011
Program:
STTR
Phase:
Phase I
Contract:
1R41HL093879-01A2
Award Id:
n/a
Agency Tracking Number:
R41HL093879
Solicitation Year:
2011
Solicitation Topic Code:
NHLBI
Solicitation Number:
PA10-051
Small Business Information
119 OVERHILL RD, BALTIMORE, MD, 21210-2724
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
796317787
Principal Investigator:
HYUNG KIM
(213) 821-2649
hyungham.kim@usc.edu
Business Contact:
THEODORE ABRAHAM
(410) 963-9451
abrahamt@innoscion.com
Research Institution:
UNIVERSITY OF SOUTHERN CALIFORNIA

UNIVERSITY OF SOUTHERN CALIFORNIA
DEPARTMENT OF CONTRACTS AND GRANTS 2001 SOTO STREET
LOS ANGELES, CA, 90089-9235
() -
Nonprofit college or university
Abstract
DESCRIPTION (provided by applicant): Safe and reliable access to major blood vessels and internal organs will be beneficial to patients with cardiovascular disease and cancer. An interventional catheter with ultrasound imaging capability will be developedto enable image-guided access to blood vessels and internal organs. Computer simulations and preliminary data using a transducer similar to that proposed for the study suggest a high likelihood of success. This Phase 1 STTR proposal seeks to develop a working prototype of the device and demonstrate feasibility of the device in its exemplary clinical uses in in-vitro gel phantoms. We will build a high frequency, small aperture forward viewing ultrasound transducer, characterize it and test it with various iterations of plastic multi-lumen catheters in a standardized gel phantom. In particular, studies will seek to demonstrate the device ability to track the device tip in real-time and guide it to specific targets in the gel phantom. This phase 1 proposal willprovide proof of concept and select the best candidate prototype for phase 2 studies. No such device is currently available in the market and the successful development of a clinically implementable device has immense commercial potential by its ability to contribute significantly to the advancement and expansion of minimally invasive medical procedures. PUBLIC HEALTH RELEVANCE: This Phase 1 STTR proposal seeks to develop a working prototype of an ultrasound guided, interventional device and to demonstrate feasibility of the device in particular exemplary clinical uses in in-vitro gel phantoms.

* information listed above is at the time of submission.

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