Development of an Active Cancellation of Tremor (ACT) System for Human Assistance

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 2R44NS070438-02
Agency Tracking Number: R44NS070438
Amount: $673,460.00
Phase: Phase II
Program: SBIR
Awards Year: 2011
Solicitation Year: 2011
Solicitation Topic Code: NINDS
Solicitation Number: PA10-050
Small Business Information
12998 ROBLEDA RD, LOS ALTOS HILLS, CA, 94022-3454
DUNS: 829976567
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 (650) 605-3687
Business Contact
Phone: (650) 605-3687
Research Institution
DESCRIPTION (provided by applicant): Essential Tremor (ET) is the single most common motion disorder, affecting 10 million people in the US alone. Due to the debilitating muscle movements associated with this disease, people with ET have difficulty in performing daily functions such as eating and drinking. As a result, many people become socially isolated and are also forced to retire from occupations held before the disease onset. Unfortunately, current pharmacological treatments have limited effectiveness in abating tremor, and surgical procedures can be expensive and invasive. To solve this problem, Lynx Design is investigating a cost-effective, lightweight, hand- held stabilization device called the ACT (Active Cancellation of Tremor) system. During Phase I work, a state- of-the-art hand-held prototype was developed and tested, demonstrating a reduction of tremor disturbances by up to 80% (for 1-2 cm). This result exceeded Phase I goals for technical feasibility and showed promise for future applications. Proposed Phase II work will focus on developing the ACT system further through a combination of clinical research and RandD. Key developments will focus on: 1) demonstrating/characterizing the technology's efficacy 2) improving control and long-term reliability and 3) designing the system for general use in daily activities (based on patient feedback). Detailed plans to commercialize the ACT system in the growing assistive device market are in place and will be executed after the Phase II work. The resulting distribution of the ACT technology will impact the growing population of ET sufferers, positively impacting their quality of life. PUBLIC HEALTH RELEVANCE: Lynx Design proposes to develop and commercialize an active tremor cancellation technology that will assist individuals affected by motion disorders such as Essential Tremor. Preliminary studies have demonstrated both feasibility of the technology and a strong unmet demand among suffering patients. The proposed system will be used to facilitate daily living, reduce social isolation, and re-enable the affected public to participate in activities and occupations that were lost upon disease onset.

* Information listed above is at the time of submission. *

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