VirtualDose Software for Diagnostic CT Doses to Adults and Children

Award Information
Agency:
Department of Health and Human Services
Branch
n/a
Amount:
$150,000.00
Award Year:
2010
Program:
STTR
Phase:
Phase I
Contract:
1R42EB010404-01
Agency Tracking Number:
R42EB010404
Solicitation Year:
2010
Solicitation Topic Code:
NIBIB
Solicitation Number:
PHS2010-2
Small Business Information
RENSSELAER POLYTECHNIC INSTITUTE
1425 CENTRAL AVE, BOX 5681, ALBANY, NY, 12205-5681
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
830026089
Principal Investigator:
XIE XU
(518) 276-4014
XUG2@RPI.EDU
Business Contact:
XIE XU
(518) 276-6283
scammr@rpi.edu
Research Institution:
Rensselaer Polytechnic Institute

110 Eighth Street
Troy, NY, 12180-3590
() -
Nonprofit college or university
Abstract
DESCRIPTION (provided by applicant): This project aims to develop a commercial software product, VirtualDoseTM, for calculating and analyzing patient radiation doses from x-ray computed tomography (CT) examinations. Despite its essential role in radiology, CT is responsible for raising the collective medical radiation dose to the American population to a level that is associated with measurable and predictable risk for carcinogenic effect today. Accurate knowledge and record of patient organ doses have now become critical in the successful and sustainable use of this imaging modality. It is recognized that existing software are insufficient in meeting the current and future needs involving modern MDCT scanners. Based on unique virtual patient technologies and extensive Monte Carlo modeling capabilities and modern software engineering, this proposed software system is expected to improve upon the accuracy and functionality in CT dose estimates. Specific aims of the project are: (1) To adopt a family of anatomically realistic phantoms including the adult male/female, pregnant female, and male/female children with the capability to adjust the body size and shape. (2) To develop a Monte Carlo based computational method for modeling various CT scanners and clinical protocols. (3) To establish a comprehensive organ dose database by using the Monte Carlo CT scanner models and ICRP algorithms. (4) To develop and refine the software graphical user interfaces by using 3D object- oriented programming. PUBLIC HEALTH RELEVANCE: A commercial software is developed to calculate and analyze patient radiation doses from x- ray computed tomography examinations using virtual patient technologies, Monte Carlo modeling and modern software engineering.

* information listed above is at the time of submission.

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