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Large depth, ultrahigh resolution, ultrahigh speed PS-OCT for burn assessment

Award Information
Agency: Department of Defense
Branch: Defense Health Program
Contract: W81XWH-11-C-0475
Agency Tracking Number: O111-H03-3050
Amount: $149,975.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: OSD11-H03
Solicitation Number: 2011.1
Solicitation Year: 2011
Award Year: 2011
Award Start Date (Proposal Award Date): 2011-08-19
Award End Date (Contract End Date): N/A
Small Business Information
15 Cabot Road
Woburn, MA -
United States
DUNS: 004841644
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Jing Ma
 Principal Engineer
 (781) 935-1200
Business Contact
 Amanda Contardo
Title: Administrative Assistant
Phone: (781) 935-1200
Research Institution

Polarization-sensitive optical coherence tomography (PS-OCT) is an imaging modality used to assess burn wound by imaging the collagen of the human skin. Agiltron propose an ultrahigh speed, ultrahigh resolution, and deep depth PS-OCT system using novel tunable laser technology. The PS-OCT imager will feature a portable design with a turn-key OCT engine and a fiber-guided handheld sample scanner. The ultrahigh resolution will enable imaging differentiation of epidermis and dermis at different skin locations with a dramatic variety of epidermis thickness. The ultrahigh speed will eliminate imaging motion artifacts and facilitate real-time imaging. The portable system enables on-site battlefield diagnosis. The well-matched depth will enable assessments of burn depth, particularly for partial-thickness burn. In particular, our system will implement polarization sensitivity for evaluation of collagen health as the specific burn biomarker. Objective and quantitative analysis will be performed by measurements of the birefringence phase retardation slope. The technical approach will be proven in Phase I through the system design and experimental testing. Completed PS-OCT system will be produced in Phase II for delivery to OSD.

* Information listed above is at the time of submission. *

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