"Point of Injury"Sampling Technology for Battlefield Molecular Diagnostics

Award Information
Agency:
Department of Defense
Branch:
Defense Advanced Research Projects Agency
Amount:
$99,811.00
Award Year:
2011
Program:
SBIR
Phase:
Phase I
Contract:
W31P4Q-11-C-0222
Agency Tracking Number:
11SB1-0026
Solicitation Year:
2011
Solicitation Topic Code:
SB111-001
Solicitation Number:
2011.1
Small Business Information
Optofluidics, Inc.
205 East Marshall Street, Ithaca, NY, -
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
963268151
Principal Investigator
 Bernardo Cordovez
 Principle Scientist&CTO
 (607) 272-2617
 cordovez@optofluidicscorp.com
Business Contact
 David Erickson
Title: President and CEO
Phone: (607) 272-2617
Email: erickson@optofluidicscorp.com
Research Institution
 Stub
Abstract
In this project Optofluidics, Inc. proposes to develop a"CLIA waivable"sample collection method for the concentration and quantification of blood-borne biomarkers associated with late phase hemorrhagic shock and traumatic brain injury. The sample collection technology is based on (1) a finger prick based assay, (2) a multistage packed bead filtration system, and (3) a novel"nanofluidic collapse"aptamer based specific protein concentration technique, originally demonstrated by the Erickson lab at Cornell University and covered under a patent application. It is proposed that this sample collection technique can be integrated with our existing Nanoscale Optofluidic Sensor Array technology to create a handheld"molecular medic"that can rapidly detect the presence of biomarkers related to these conditions. With our devices untrained personnel or first responders could diagnose with better certainty the presence of these injuries and make more informed decisions regarding treatment, having a dramatic influence on outcomes following a traumatic event.

* information listed above is at the time of submission.

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