Artificial Tissue Matrices for Bone Repair

Award Information
Agency:
Department of Defense
Branch
n/a
Amount:
$70,000.00
Award Year:
2011
Program:
SBIR
Phase:
Phase I
Contract:
N00014-11-M-0113
Agency Tracking Number:
N102-179-0359
Solicitation Year:
2010
Solicitation Topic Code:
N102-179
Solicitation Number:
2010.2
Small Business Information
MO-SCI Corporation
4040 Hypoint North, Rolla, MO, -
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
190717025
Principal Investigator:
Mariano Velez
R&D Senior Engineer
(573) 364-2338
mvelez@mo-sci.com
Business Contact:
Thomas Day
President
(573) 364-2338
tday@mo-sci.com
Research Institution:
Stub




Abstract
This Small Business Innovation Research (SBIR) by Mo-Sci Corporation in collaboration with the Indiana University School of Dentistry (IU) and the Missouri University of Science & Technology (Missouri S & T) proposes to use bioactive glass bone scaffolds for bone repair. The objective is to develop a completely artificial bone substitute material that mimics human bone and can replace long bones, facial bones and skull bones. The new bioactive glass scaffolds are biodegradable and biocompatible and are synergistic with the natural bone tissue regeneration process. The scaffolds are manufactured by selective laser sintering (SLS), to mimic the structure and mechanical properties of normal healthy trabecular bone tissue, and with good capability for vascularization. The bioactive glass scaffolds will be tested if can function as carrier for Bone Morphogenic Protein-2 (BMP-2) and induce bone healing in small animals in Phase I. Mo-Sci Corp. will develop the SLS scaffolds as Intellectual Property, then work with the American Medical Association and the Food and Drug Administration (FDA) to gain the necessary approvals to begin making the SLS bone scaffolds available to greater medical community.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government