Artificial Tissue Matrices for Bone Repair

Award Information
Agency: Department of Defense
Branch: Navy
Contract: N00014-11-M-0113
Agency Tracking Number: N102-179-0359
Amount: $70,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2011
Solicitation Year: 2010
Solicitation Topic Code: N102-179
Solicitation Number: 2010.2
Small Business Information
4040 Hypoint North, Rolla, MO, -
DUNS: 190717025
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Mariano Velez
 R&D Senior Engineer
 (573) 364-2338
Business Contact
 Thomas Day
Title: President
Phone: (573) 364-2338
Research Institution
This Small Business Innovation Research (SBIR) by Mo-Sci Corporation in collaboration with the Indiana University School of Dentistry (IU) and the Missouri University of Science & Technology (Missouri S & T) proposes to use bioactive glass bone scaffolds for bone repair. The objective is to develop a completely artificial bone substitute material that mimics human bone and can replace long bones, facial bones and skull bones. The new bioactive glass scaffolds are biodegradable and biocompatible and are synergistic with the natural bone tissue regeneration process. The scaffolds are manufactured by selective laser sintering (SLS), to mimic the structure and mechanical properties of normal healthy trabecular bone tissue, and with good capability for vascularization. The bioactive glass scaffolds will be tested if can function as carrier for Bone Morphogenic Protein-2 (BMP-2) and induce bone healing in small animals in Phase I. Mo-Sci Corp. will develop the SLS scaffolds as Intellectual Property, then work with the American Medical Association and the Food and Drug Administration (FDA) to gain the necessary approvals to begin making the SLS bone scaffolds available to greater medical community.

* Information listed above is at the time of submission. *

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government