Artificial Tissue Matrices for Bone Repair

Award Information
Agency: Department of Defense
Branch: Navy
Contract: N00014-11-M-0115
Agency Tracking Number: N102-179-0381
Amount: $62,584.00
Phase: Phase I
Program: SBIR
Awards Year: 2011
Solicitation Year: 2010
Solicitation Topic Code: N102-179
Solicitation Number: 2010.2
Small Business Information
216 Howard Street, New London, CT, -
DUNS: 827152666
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 James O'Malley
 (860) 884-4070
Business Contact
 James O'Malley
Title: Owner
Phone: (860) 884-4070
Research Institution
The injuries to warfighters caused by Improved Explosive Devices and snipers are often associated with significant loss of long and/or maxillofacial bones. Effective treatment and recuperation necessitates the replacement of these missing bone structures. We are developing a device which once implanted into the injury defect will strongly stimulate osteogenesis and ultimately be resorbed and replaced by the patient"s own bone over one to four months, depending on the size of the injury. By stimulating de novo bone formation and filling the defect with the patient"s own bone many of the post operative complications associated with current therapies will be overcome. This treatment is currently being developed for flat bones such as cranium and maxillofacial, however it will also be effective in long bone. In addition the bioactive component of this device can be applied to prosthetics to increase osseointegration to increase both the rate and quality of recovery.

* Information listed above is at the time of submission. *

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