SBIR Phase I: Novel Advanced Nematicides with Improved Efficacy and Safety

Award Information
Agency:
National Science Foundation
Branch
n/a
Amount:
$150,000.00
Award Year:
2010
Program:
SBIR
Phase:
Phase I
Contract:
0944853
Agency Tracking Number:
0944853
Solicitation Year:
n/a
Solicitation Topic Code:
CT.
Solicitation Number:
n/a
Small Business Information
Divergence
1005 North Warson Road, Suite 401, Saint Louis, MO, 63132
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
072669828
Principal Investigator:
Urszula Slomczynska
MEE
(314) 812-8024
slomczynska@divergence.com
Business Contact:
Urszula Slomczynska
MEE
(314) 812-8024
slomczynska@divergence.com
Research Institution:
n/a
Abstract
This SBIR Phase I project will develop novel nematicides using proprietary chemical design and screening methods. The project will first design, prioritize, and synthesize a set of entirely novel molecules. The project will then evaluate compounds for activity in multiple biological assays with parasitic nematodes and plants. Promising scaffolds will be prioritized for further development in Phase II including assessment of toxicity, manufacturing cost, and additional synthetic opportunities. The broader/commercial impact of the project will be to protect crops against nematodes which result in significant benefit to growers and the environment. The potential value to Divergence is very large, with the current nematicide market of $1 billion under representing the actual value that could be generated. REsulting effective nematicides with superior safety to current prodicts will be of immediate benefit to growers, consumers, and the environment.

* information listed above is at the time of submission.

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