Novel Agrochemical Leads Derived from Molecular Fields

Award Information
Agency:
Department of Agriculture
Branch
n/a
Amount:
$400,000.00
Award Year:
2010
Program:
SBIR
Phase:
Phase II
Contract:
n/a
Agency Tracking Number:
2010-02166
Solicitation Year:
n/a
Solicitation Topic Code:
8.2
Solicitation Number:
n/a
Small Business Information
DIVERGENCE, INC.
1005 N WARSON RD, Saint Louis, MO, 63132
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
072669828
Principal Investigator:
Michael Crawford
Director
(314) 812-8087
crawford@divergence.com
Business Contact:
Michelle Insco
Senior Director
(314) 812-8024
insco@divergence.com
Research Institution:
n/a
Abstract
An estimated one-third of worldwide crop production is lost to pathogens including fungi. Despite advances in chemical control, the onset of resistance limits the utility of current fungicides. In addition, most pesticide research projects are terminated because of unattractive attributes of the lead chemical series, such as toxicity, manufacturing cost, or a crowded intellectual property landscape, which cannot be engineered out of the molecule. It is therefore desirable to identify alternate chemical scaffolds that retain the desired fungicidal spectrum and MOA while improving other characteristics. The proposed work is expected to result in a safe and efficacious fungicidal lead with a novel MOA that will be highly beneficial to growers, consumers, and the environment and economically attractive to commercial partners. Use of such a fungicide as part of an Integrated Pest Management program could replace older compounds with unfavorable environmental toxicity and prevent resistance development among newer fungicide classes.

* information listed above is at the time of submission.

Agency Micro-sites


SBA logo

Department of Agriculture logo

Department of Commerce logo

Department of Defense logo

Department of Education logo

Department of Energy logo

Department of Health and Human Services logo

Department of Homeland Security logo

Department of Transportation logo

Enviromental Protection Agency logo

National Aeronautics and Space Administration logo

National Science Foundation logo
US Flag An Official Website of the United States Government