Rapid, Field Deployable Alphavirus and Flavivirus Identification Assay

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-11-C-0034
Agency Tracking Number: A103-158-0010
Amount: $70,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2011
Solicitation Year: 2010
Solicitation Topic Code: A10-158
Solicitation Number: 2010.3
Small Business Information
999 Lehigh Station Rd, Henrietta, NY, -
DUNS: 059633672
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Richard Murante
 Sr Research Scientist
 (585) 334-0170
 rmurante@integratednano.com
Business Contact
 Michael Connolly
Title: CEO and President
Phone: (585) 334-0170
Email: mconnolly@integratednano.com
Research Institution
 Stub
Abstract
Integrated Nano-technologies has developed a method that identifies pathogens using nucleic acid information. The technology has been developed into a prototype system consisting of a analyzer device, a unique single-use cartridge in which the entire preparation and identification processes take place, and a microchip on which the identification occurs. The prototype meets many of the requirements of this solicitation. The primary objective of this project is to advance to commercialization a rapid, field-deployable assay designed to identify a range of medically relevant alphaviruses and flaviviruses from arthropod sources. The assay will be able to meet the key needs requested by this solicitation: - will be the size of a handheld electronic device, and weigh less than three pounds. - provides a results read-out in about ten minutes, - is cost affordable - has simple operator requirements, including for sample preparation - uses standard, heat stable reagents and materials that do not require special preparation for use, - runs on batteries - is at least 80% as specific and 80% as sensitive as the current gold-standard assays (e.g. PCR, ELISA) for the individual viruses. Phase I will evaluate the feasibility of the prototype system to work with five viruses and meet the operational requirements of the solicitation.

* Information listed above is at the time of submission. *

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