Ultrasound for neuromodulation and control of post-trauma pain

Award Information
Agency: Department of Defense
Branch: Army
Contract: W911NF-11-C-0204
Agency Tracking Number: A111-020-0696
Amount: $100,000.00
Phase: Phase I
Program: SBIR
Awards Year: 2011
Solicitation Year: 2011
Solicitation Topic Code: A11-020
Solicitation Number: 2011.1
Small Business Information
DUNS: 006056296
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Sumon Pal
 Chief Technology Officer
 (412) 414-0187
Business Contact
 Sumon Pal
Title: Chief Technology Officer
Phone: (412) 414-0187
Email: spal@synsonix.com
Research Institution
The objective of this proposal is to demonstrate the feasibility of using ultrasound induced neuromodulation to manage pain. SynSonix, LLC has been developing ultrasound neuromodulation (UNMOD) to noninvasively stimulate neural circuitry. Many studies have established the beneficial effects of neurostimulation for managing pain. However current methodologies require surgical implantation of stimulating electrodes which is an impractical solution for acute traumas. Pain management for acute traumas is generally accomplished with narcotics, which is less than ideal in a battlefield scenario as they severely effect cognitive abilities and have other unwanted side effects such as respiratory depression. Our technology of peripheral ultrasound neuromodulation (PUNMOD) offers several advantages over narcotics and current methods of neurostimulation. PUNMOD has the potential to be highly portable as a battlefield analgesic and has the advantage of leaving the patients cognitive abilities intact. In addition PUNMOD does not carry with it the risk of abuse or the need for the surveillance that is associated with pharmaceutical analgesics. In this proposal we outline a plan for the development and testing of a portable, first-generation prototype capable of noninvasive peripheral neurostimulation to modulate pain.

* Information listed above is at the time of submission. *

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