Raman Anthrax and Biothreat Detection System (RADS)

Award Information
Agency:
Department of Defense
Branch
Army
Amount:
$148,890.00
Award Year:
2011
Program:
SBIR
Phase:
Phase I
Contract:
W911NF-11-C-0203
Agency Tracking Number:
A111-021-1167
Solicitation Year:
2011
Solicitation Topic Code:
A11-021
Solicitation Number:
2011.1
Small Business Information
Spectral Platforms
5652 Stardust Road, La Canada, CA, -
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
962639931
Principal Investigator:
Ravi Verma
CEO
(626) 532-7284
rverma@spectralplatforms.com
Business Contact:
Ravi Verma
CEO
(626) 532-7284
rverma@spectralplatforms.com
Research Institution:
Stub




Abstract
Since the anthrax attacks of September-October 2001, the United States has developed and deployed several biothreat detection systems (most notably at various postal service locations). The most accurate systems utilize PCR technology and are therefore bulky, cannot be easily miniaturized, and generally are not suitable for detection in more remote locations. Smaller systems, such as those based on the detection of spores via standard Raman spectroscopy or by use of immunoassays result in an unacceptable high proportion of falsely positive signals, thereby limiting their utility. Here, we propose a highly specific bioterror threat agent detection system using ultraviolet light emitting diodes (UV LED) in a Raman spectrometer, combined with a 2D correlation analytic technique. In Phase I, we will validate our methods with experimental results collected using a breadboard instrument on an accepted anthrax simulant. We will demonstrate that our methods improve the detection sensitivity by 100,000-fold compared to the current approach for point-of-care detection. In Phase II, we will implement our technique in a compact point-of-care instrument ready for CONUS testing at an Army facility.

* information listed above is at the time of submission.

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