Raman Anthrax and Biothreat Detection System (RADS)

Award Information
Agency: Department of Defense
Branch: Army
Contract: W911NF-11-C-0203
Agency Tracking Number: A111-021-1167
Amount: $148,890.00
Phase: Phase I
Program: SBIR
Awards Year: 2011
Solicitation Year: 2011
Solicitation Topic Code: A11-021
Solicitation Number: 2011.1
Small Business Information
5652 Stardust Road, La Canada, CA, -
DUNS: 962639931
HUBZone Owned: N
Woman Owned: N
Socially and Economically Disadvantaged: N
Principal Investigator
 Ravi Verma
 (626) 532-7284
Business Contact
 Ravi Verma
Title: CEO
Phone: (626) 532-7284
Email: rverma@spectralplatforms.com
Research Institution
Since the anthrax attacks of September-October 2001, the United States has developed and deployed several biothreat detection systems (most notably at various postal service locations). The most accurate systems utilize PCR technology and are therefore bulky, cannot be easily miniaturized, and generally are not suitable for detection in more remote locations. Smaller systems, such as those based on the detection of spores via standard Raman spectroscopy or by use of immunoassays result in an unacceptable high proportion of falsely positive signals, thereby limiting their utility. Here, we propose a highly specific bioterror threat agent detection system using ultraviolet light emitting diodes (UV LED) in a Raman spectrometer, combined with a 2D correlation analytic technique. In Phase I, we will validate our methods with experimental results collected using a breadboard instrument on an accepted anthrax simulant. We will demonstrate that our methods improve the detection sensitivity by 100,000-fold compared to the current approach for point-of-care detection. In Phase II, we will implement our technique in a compact point-of-care instrument ready for CONUS testing at an Army facility.

* Information listed above is at the time of submission. *

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