A Chip-Scale Sensor for High-Throughput Detection of Multiple Waterborne Pathogens

Award Information
Agency:
Department of Defense
Branch
Defense Advanced Research Projects Agency
Amount:
$749,998.00
Award Year:
2011
Program:
SBIR
Phase:
Phase II
Contract:
D11PC20171
Agency Tracking Number:
09SB3-0175
Solicitation Year:
2009
Solicitation Topic Code:
SB093-010
Solicitation Number:
2009.3
Small Business Information
Real-Time Analyzers
362 Industrial Park Road, Suite #8, Middletown, CT, -
Hubzone Owned:
N
Socially and Economically Disadvantaged:
N
Woman Owned:
N
Duns:
076890222
Principal Investigator:
Frank Inscore
Director of Raman Applica
(860) 635-9800
inscore@rta.biz
Business Contact:
Stuart Farquharson
President
(860) 635-9800
stu@rta.biz
Research Institution:
Stub




Abstract
The overall goal of this proposed program (through Phase III) is to develop a chip-scale assay that can detect, identify, and quantify the presence of Category A (or B) bioagents in water at the required sensitivity (e.g. 8000 B. anthracis spores or 50µg of ricin per liter water) within 10 minutes. During the Phase I program feasibility was demonstrated by successfully detecting the capture of less than 10 Bacillus anthracis-Sterne (BAS) spores in under 15 minutes by surface-enhanced Raman spectroscopy (SERS). During the Phase II program, a prototype Portable Bioagent Water Analyzer capable of detecting as many as 10 different bioagents in water within 10 minutes at the required sensitivity and specificity. Actual Category A bioagents will be measured at the US Army"s Edgwood Chem Bio Center for component testing in Phase II and prototype testing in Phase III to bring the prototype to a technology transition level of 6.

* information listed above is at the time of submission.

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