Nanosensor Cartridge for Bioagent Detection within Geospatial Networked Motes

Award Information
Agency:
Department of Defense
Branch
n/a
Amount:
$1,318,309.00
Award Year:
2011
Program:
SBIR
Phase:
Phase II
Contract:
W9132V-10-C-0001
Award Id:
n/a
Agency Tracking Number:
A2-3928
Solicitation Year:
2008
Solicitation Topic Code:
A08-169
Solicitation Number:
2008.3
Small Business Information
4401 Dayton-Xenia Road, Dayton, OH, -
Hubzone Owned:
N
Minority Owned:
N
Woman Owned:
N
Duns:
074689217
Principal Investigator:
MelanieTomczak
Research Scientist
(937) 426-6900
mtomczak@ues.com
Business Contact:
BryceSkinn
Business Relations Manage
(937) 426-6900
bskinn@ues.com
Research Institute:
Stub




Abstract
Detection of biological warfare agents in a real-world setting is an increasingly urgent problem. Many of the current state-of-the-art sensors require large biomolecules, such as antibodies, to achieve binding of the target molecule and subsequent reporting of the binding event. This type of detection is not stable under deployed environmental conditions and often requires blocking and washing steps. These technical hurdles are a drawback when considering use of these technologies in a battlefield situation. Here, we propose a sensor that is based on stable biomolecules that act as ligands for the target(s) of interest. Due to their small size, these ligands are not susceptible to conformational instability and the sensors should have a long lifetime even when deployed. Additionally, the sensor incorporates an exponential amplification of the output signal when the target of interest binds, effectively eliminating the background and false positive results.

* information listed above is at the time of submission.

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